Methyldopa and Ascites - a phase IV clinical study of FDA data

Summary:

Ascites is reported as a side effect among people who take Methyldopa (methyldopa), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Procainamide Hydrochloride, and have Foetal exposure during pregnancy.

The phase IV clinical study analyzes which people have Ascites when taking Methyldopa. It is created by eHealthMe based on reports of 6,345 people who have side effects when taking Methyldopa from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Ascites?

Ascites (accumulation of fluid in the abdominal cavity) is found to be associated with 1,528 drugs and 2,026 conditions by eHealthMe. Check the latest studies of Ascites.



On Jul, 06, 2026

6,345 people reported to have side effects when taking Methyldopa.
Among them, 46 people (0.72%) have Ascites.

Could Methyldopa cause Ascites?

Among these 46 people:

How long have people been on Methyldopa when they have Ascites? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ascites when taking Methyldopa? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Ascites when taking Methyldopa? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 72.22 %
  • 30-39: 8.33 %
  • 40-49: 11.11 %
  • 50-59: 2.78 %
  • 60+: 5.56 %

What are other drugs people take besides Methyldopa? *

  1. Humira: 30 people, 65.22%
  2. Voriconazole: 30 people, 65.22%
  3. Procainamide Hydrochloride: 30 people, 65.22%
  4. Minocycline: 19 people, 41.30%
  5. Quinidine Sulfate: 17 people, 36.96%
  6. Hydralazine Hydrochloride: 12 people, 26.09%
  7. Chlorpromazine Hydrochloride: 12 people, 26.09%
  8. Minocycline Hydrochloride: 11 people, 23.91%
  9. Lamisil: 10 people, 21.74%
  10. Hydroxychloroquine Sulfate: 6 people, 13.04%

What are other side effects people have besides Ascites? *

  1. Pleural Effusion (water on the lungs): 40 people, 86.96%
  2. Maternal Exposure During Pregnancy (use of substance during pregnancy): 33 people, 71.74%
  3. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 31 people, 67.39%
  4. Infection: 30 people, 65.22%
  5. Premature Menopause: 30 people, 65.22%
  6. Venous Thrombosis Limb (blood clot that forms in a vein in the limb): 30 people, 65.22%
  7. Lupus-Like Syndrome (a disease symptom matches with lupus an immune disease): 30 people, 65.22%
  8. Pain: 30 people, 65.22%
  9. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 30 people, 65.22%
  10. Cardiac Tamponade (fluid accumulates in heart covering): 30 people, 65.22%

What are the existing conditions these people have? *

  1. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 4.35%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 2.17%
  3. Pre-Eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman): 1 person, 2.17%
  4. Hypertensive Nephropathy (hypertensive renal disease): 1 person, 2.17%
  5. Gestational Hypertension (elevated blood pressure during pregnancy): 1 person, 2.17%
  6. Foetal Disorder (fetus disease): 1 person, 2.17%
  7. Essential Hypertension (primary hypertension): 1 person, 2.17%
  8. Diabetes: 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Methyldopa and have Ascites?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methyldopa:

Ascites treatments and more:

How severe was Ascites and when was it recovered:

Expand to all the drugs that have ingredients of methyldopa:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ascites:

Browse all the conditions that are associated with Ascites:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methyldopa (the active ingredients of Methyldopa) and Methyldopa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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