Avalide and Ischaemic stroke - a phase IV clinical study of FDA data

Summary:

Ischaemic stroke is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lipitor, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Ischaemic stroke when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Ischaemic stroke?

Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain) is found to be associated with 848 drugs and 1,095 conditions by eHealthMe. Check the latest studies of Ischaemic stroke.

On Aug, 06, 2026

5,642 people reported to have side effects when taking Avalide.
Among them, 15 people (0.27%) have Ischaemic stroke.

Among these 15 people:

How long have people been on Avalide when they have Ischaemic stroke? *

What is the gender of people who have Ischaemic stroke when taking Avalide? *

female: 53.33 %
male: 46.67 %

What is the age of people who have Ischaemic stroke when taking Avalide? *

What are other drugs people take besides Avalide? *

What are other side effects people have besides Ischaemic stroke? *

Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 20.00%
Central Pain Syndrome (neurological condition caused by damage or malfunction in the central nervous system): 3 people, 20.00%
Drug Ineffective: 3 people, 20.00%
Visual Impairment: 2 people, 13.33%
Atherosclerosis (disorder of the arteries): 2 people, 13.33%
Blood Magnesium Decreased: 2 people, 13.33%
Blood Potassium Decreased: 2 people, 13.33%
Blood Sodium Decreased: 2 people, 13.33%
Headache (pain in head): 2 people, 13.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.67%

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 33.33%
Osteoporosis (bones weak and more likely to break): 5 people, 33.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 33.33%
High Blood Cholesterol: 5 people, 33.33%
Heart Disease: 5 people, 33.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 33.33%
Pain: 3 people, 20.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 20.00%
Dyspnea (difficult or laboured breathing): 3 people, 20.00%
Central Pain Syndrome (neurological condition caused by damage or malfunction in the central nervous system): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Ischaemic stroke?

- Check whether Ischaemic stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Ischaemic stroke treatments and more:

Ischaemic stroke (25,786 reports)

How severe was Ischaemic stroke and when was it recovered:

Ischaemic stroke in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Ischaemic stroke and drugs with ingredients of hydrochlorothiazide; irbesartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ischaemic stroke:

Ischaemic stroke (848 drugs)

Browse all the conditions that are associated with Ischaemic stroke:

Ischaemic stroke (1,095 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.