Avalide and Multiple sclerosis aggravated - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis aggravated is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are male, 50-59 old, also take Aspirin, and have Arthropathy.

The phase IV clinical study analyzes which people have Multiple sclerosis aggravated when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Multiple sclerosis aggravated?

Multiple sclerosis aggravated (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,023 drugs and 323 conditions by eHealthMe. Check the latest studies of Multiple sclerosis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

5,642 people reported to have side effects when taking Avalide.
Among them, 12 people (0.21%) have Multiple sclerosis aggravated.

Could Avalide cause Multiple sclerosis aggravated?

Among these 12 people:

What is the gender of people who have Multiple sclerosis aggravated when taking Avalide? *

female: 50 %
male: 50 %

What is the age of people who have Multiple sclerosis aggravated when taking Avalide? *

What are other drugs people take besides Avalide? *

What are other side effects people have besides Multiple sclerosis aggravated? *

Dizziness: 6 people, 50.00%
Gait Disturbance: 4 people, 33.33%
Fall: 4 people, 33.33%
Retching (strong involuntary effort to vomit): 3 people, 25.00%
Feeling Abnormal: 3 people, 25.00%
Metastases To Lymph Nodes (cancer spreads to lymph node): 3 people, 25.00%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 25.00%
Nausea And Vomiting: 3 people, 25.00%
Pain: 3 people, 25.00%
Memory Loss: 3 people, 25.00%

What are the existing conditions these people have? *

Depressed Mood: 3 people, 25.00%
Arthropathy: 3 people, 25.00%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 2 people, 16.67%
Movement - Uncoordinated: 2 people, 16.67%
Gait Disturbance: 2 people, 16.67%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 16.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 8.33%
Joint Pain: 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Hearing Loss: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Multiple sclerosis aggravated?

- Check whether Multiple sclerosis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Multiple sclerosis aggravated treatments and more:

Multiple sclerosis aggravated (1,779 reports)

How severe was Multiple sclerosis aggravated and when was it recovered:

Multiple sclerosis aggravated in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Multiple sclerosis aggravated and drugs with ingredients of hydrochlorothiazide; irbesartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (1,023 drugs)

Browse all the conditions that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (323 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.