Avandaryl and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Avandaryl (glimepiride; rosiglitazone maleate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Avandia, and have Indigestion.

The phase IV clinical study analyzes which people have Joint pain when taking Avandaryl. It is created by eHealthMe based on reports of 2,654 people who have side effects when taking Avandaryl from the FDA, and is updated regularly.

What is Avandaryl?

Avandaryl has active ingredients of glimepiride; rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 2,660 Avandaryl users. Check the latest studies of Avandaryl.

What is Joint pain?

Joint pain is found to be associated with 3,330 drugs and 5,207 conditions by eHealthMe. Check the latest studies of Joint pain.

On Jul, 18, 2026

2,654 people reported to have side effects when taking Avandaryl.
Among them, 13 people (0.49%) have Joint pain.

Among these 13 people:

How long have people been on Avandaryl when they have Joint pain? *

What is the gender of people who have Joint pain when taking Avandaryl? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Joint pain when taking Avandaryl? *

What are other drugs people take besides Avandaryl? *

What are other side effects people have besides Joint pain? *

Rashes (redness): 6 people, 46.15%
Dizziness: 5 people, 38.46%
Weakness: 5 people, 38.46%
Pain: 5 people, 38.46%
Oedema Peripheral (superficial swelling): 5 people, 38.46%
Deformity (disfigurement): 5 people, 38.46%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 30.77%
Neck Pain: 4 people, 30.77%
Nausea (feeling of having an urge to vomit): 4 people, 30.77%
Multiple Injuries: 4 people, 30.77%

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 15.38%
Indigestion: 2 people, 15.38%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Lipids Abnormal: 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Avandaryl and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avandaryl:

Avandaryl (2,660 reports)

Joint pain treatments and more:

Joint pain (542,934 reports)

How severe was Joint pain and when was it recovered:

Joint pain in Avandaryl

Expand to all the drugs that have ingredients of glimepiride; rosiglitazone maleate:

Joint pain and drugs with ingredients of glimepiride; rosiglitazone maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avandaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,330 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,207 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride; rosiglitazone maleate (the active ingredients of Avandaryl) and Avandaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.