Aviane-28 and Hypercorticoidism - a phase IV clinical study of FDA data

Summary:

Hypercorticoidism is reported as a side effect among people who take Aviane-28 (ethinyl estradiol; levonorgestrel), especially for people who are female, also take Reglan, and have Osteoporosis.

The phase IV clinical study analyzes which people have Hypercorticoidism when taking Aviane-28. It is created by eHealthMe based on reports of 150 people who have side effects when taking Aviane-28 from the FDA, and is updated regularly.

What is Aviane-28?

Aviane-28 has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 286 Aviane-28 users. Check the latest studies of Aviane-28.

What is Hypercorticoidism?

Hypercorticoidism (excessive secretion of one or more steroid hormones of the adrenal cortex) is found to be associated with 35 drugs and 75 conditions by eHealthMe. Check the latest studies of Hypercorticoidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

150 people reported to have side effects when taking Aviane-28.
Among them, 13 people (8.67%) have Hypercorticoidism.

Could Aviane-28 cause Hypercorticoidism?

Among these 13 people:

What is the gender of people who have Hypercorticoidism when taking Aviane-28? *

female: 100 %
male: 0.0 %

What are other drugs people take besides Aviane-28? *

What are other side effects people have besides Hypercorticoidism? *

Weight Decreased: 13 people, 100.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 13 people, 100.00%
Facet Joint Syndrome (problem with movement of the facet joints of the spine): 13 people, 100.00%
Facial Pain: 13 people, 100.00%
Failure To Thrive (inadequate weight gain and physical growth in children): 13 people, 100.00%
Fall: 13 people, 100.00%
Feeling Abnormal: 13 people, 100.00%
Fibrocystic Breast Disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women): 13 people, 100.00%
Gastritis (inflammation of stomach): 13 people, 100.00%
Hair Loss: 13 people, 100.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 13 people, 100.00%
Sinus Disorder (disease of sinus): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aviane-28 and have Hypercorticoidism?

- Check whether Hypercorticoidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aviane-28:

Aviane-28 (286 reports)

Hypercorticoidism treatments and more:

Hypercorticoidism (245 reports)

How severe was Hypercorticoidism and when was it recovered:

Hypercorticoidism in Aviane-28

Expand to all the drugs that have ingredients of ethinyl estradiol; levonorgestrel:

Hypercorticoidism and drugs with ingredients of ethinyl estradiol; levonorgestrel (14 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aviane-28:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercorticoidism:

Hypercorticoidism (35 drugs)

Browse all the conditions that are associated with Hypercorticoidism:

Hypercorticoidism (75 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; levonorgestrel (the active ingredients of Aviane-28) and Aviane-28 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.