Avonex and Extrapyramidal disorder - a phase IV clinical study of FDA data

Summary:

Extrapyramidal disorder is reported as a side effect among people who take Avonex (interferon beta 1a), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Metoclopramide, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Extrapyramidal disorder when taking Avonex. It is created by eHealthMe based on reports of 198,141 people who have side effects when taking Avonex from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Extrapyramidal disorder?

Extrapyramidal disorder (involuntary muscle spasms in the face and neck) is found to be associated with 813 drugs and 960 conditions by eHealthMe. Check the latest studies of Extrapyramidal disorder.



On Jul, 11, 2026

198,141 people reported to have side effects when taking Avonex.
Among them, 22 people (0.01%) have Extrapyramidal disorder.

Could Avonex cause Extrapyramidal disorder?

Among these 22 people:

How long have people been on Avonex when they have Extrapyramidal disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Extrapyramidal disorder when taking Avonex? *

  • female: 85.71 %
  • male: 14.29 %

What is the age of people who have Extrapyramidal disorder when taking Avonex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 23.08 %
  • 40-49: 38.46 %
  • 50-59: 23.08 %
  • 60+: 15.38 %

What are other drugs people take besides Avonex? *

  1. Metoclopramide: 9 people, 40.91%
  2. Tysabri: 6 people, 27.27%
  3. Neurontin: 4 people, 18.18%
  4. Reglan: 4 people, 18.18%
  5. Benadryl: 3 people, 13.64%
  6. Baclofen: 3 people, 13.64%
  7. Zoloft: 2 people, 9.09%
  8. Aggrenox: 2 people, 9.09%
  9. Nitroglycerin: 2 people, 9.09%
  10. Ranitidine: 2 people, 9.09%

What are other side effects people have besides Extrapyramidal disorder? *

  1. Tardive Dyskinesia (a disorder that involves involuntary movements): 11 people, 50.00%
  2. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 5 people, 22.73%
  3. Memory Loss: 5 people, 22.73%
  4. Movement - Uncontrolled Or Slow: 5 people, 22.73%
  5. Fatigue (feeling of tiredness): 5 people, 22.73%
  6. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 18.18%
  7. Stress And Anxiety: 4 people, 18.18%
  8. Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 18.18%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 18.18%
  10. Gait Disturbance: 4 people, 18.18%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
  2. Indigestion: 2 people, 9.09%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 4.55%
  4. Pain: 1 person, 4.55%
  5. Embolism Arterial (blood clot that has travelled through your arteries and become stuck): 1 person, 4.55%
  6. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 1 person, 4.55%
  7. Confusional State: 1 person, 4.55%
  8. Abdominal Distension: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Avonex and have Extrapyramidal disorder?

- Check whether Extrapyramidal disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avonex:

Extrapyramidal disorder treatments and more:

How severe was Extrapyramidal disorder and when was it recovered:

Expand to all the drugs that have ingredients of interferon beta 1a:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avonex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrapyramidal disorder:

Browse all the conditions that are associated with Extrapyramidal disorder:


How the study uses the data?

The study uses data from the FDA. It is based on interferon beta 1a (the active ingredients of Avonex) and Avonex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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