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Axid and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Axid (nizatidine), especially for people who are female, 60+ old, also take Vioxx, and have Pain.

The phase IV clinical study analyzes which people have Stroke when taking Axid. It is created by eHealthMe based on reports of 2,951 people who have side effects when taking Axid from the FDA, and is updated regularly.

What is Axid?

Axid has active ingredients of nizatidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,980 Axid users. Check the latest studies of Axid.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,360 drugs and 3,019 conditions by eHealthMe. Check the latest studies of Stroke.

On Dec, 20, 2025

2,951 people reported to have side effects when taking Axid.
Among them, 37 people (1.25%) have Stroke.

Could Axid cause Stroke?

Among these 37 people:

What is the gender of people who have Stroke when taking Axid? *

  • female: 55.88 %
  • male: 44.12 %

What is the age of people who have Stroke when taking Axid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 11.76 %
  • 40-49: 8.82 %
  • 50-59: 23.53 %
  • 60+: 55.88 %

What are other drugs people take besides Axid? *

  1. Vioxx: 17 people, 45.95%
  2. Lipitor: 12 people, 32.43%
  3. Nexium: 9 people, 24.32%
  4. Prilosec: 8 people, 21.62%
  5. Norvasc: 7 people, 18.92%
  6. Protonix: 7 people, 18.92%
  7. Zantac: 7 people, 18.92%
  8. Pepcid: 6 people, 16.22%
  9. Nexium 24hr: 6 people, 16.22%
  10. Dexlansoprazole: 6 people, 16.22%

What are other side effects people have besides Stroke? *

  1. Depression: 11 people, 29.73%
  2. Acute Kidney Failure: 11 people, 29.73%
  3. Stress And Anxiety: 11 people, 29.73%
  4. Chest Pain: 8 people, 21.62%
  5. Osteoporosis (bones weak and more likely to break): 7 people, 18.92%
  6. Suicidal Ideation: 7 people, 18.92%
  7. Emotional Distress: 7 people, 18.92%
  8. Weakness: 6 people, 16.22%
  9. Mania (a state of abnormally elevated or irritable mood): 6 people, 16.22%
  10. Neoplasm Malignant (cancer tumour): 6 people, 16.22%

What are the existing conditions these people have? *

  1. Pain: 6 people, 16.22%
  2. Nausea And Vomiting: 4 people, 10.81%
  3. Gastric Infection (infection of stomach): 4 people, 10.81%
  4. Costochondritis (chest wall pain): 4 people, 10.81%
  5. Nausea (feeling of having an urge to vomit): 4 people, 10.81%
  6. Infection: 4 people, 10.81%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 8.11%
  8. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 5.41%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
  10. Osteoporosis (bones weak and more likely to break): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Axid and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Axid:

  • Axid (2,980 reports)

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of nizatidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Axid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:

How the study uses the data?

The study uses data from the FDA. It is based on nizatidine (the active ingredients of Axid) and Axid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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