Ayvakit and Neoplasm malignant - a phase IV clinical study of FDA data

Summary:

Neoplasm malignant is reported as a side effect among people who take Ayvakit (avapritinib), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Prochlorperazine, and have Gastrointestinal stromal tumor.

The phase IV clinical study analyzes which people have Neoplasm malignant when taking Ayvakit. It is created by eHealthMe based on reports of 7,362 people who have side effects when taking Ayvakit from the FDA, and is updated regularly.

What is Ayvakit?

Ayvakit has active ingredients of avapritinib. eHealthMe is studying from 7,362 Ayvakit users. Check the latest studies of Ayvakit.

What is Neoplasm malignant?

Neoplasm malignant (cancer tumour) is found to be associated with 1,541 drugs and 1,261 conditions by eHealthMe. Check the latest studies of Neoplasm malignant.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

7,362 people reported to have side effects when taking Ayvakit.
Among them, 32 people (0.43%) have Neoplasm malignant.

Among these 32 people:

How long have people been on Ayvakit when they have Neoplasm malignant? *

What is the gender of people who have Neoplasm malignant when taking Ayvakit? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Neoplasm malignant when taking Ayvakit? *

What are other drugs people take besides Ayvakit? *

What are other side effects people have besides Neoplasm malignant? *

Drug Ineffective: 9 people, 28.12%
Diarrhea: 7 people, 21.88%
Nausea And Vomiting: 6 people, 18.75%
Fatigue (feeling of tiredness): 5 people, 15.62%
Memory Loss: 4 people, 12.50%
Haemoglobin Decreased: 3 people, 9.38%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 9.38%
Nausea (feeling of having an urge to vomit): 3 people, 9.38%
Tumor: 3 people, 9.38%
Dizziness: 3 people, 9.38%

What are the existing conditions these people have? *

Gastrointestinal Stromal Tumor: 22 people, 68.75%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 9 people, 28.12%
Dyspnea (difficult or laboured breathing): 2 people, 6.25%
Sleep Disorder: 1 person, 3.12%
Pain: 1 person, 3.12%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.12%
Diabetes: 1 person, 3.12%
Delirium (wild excitement): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Ayvakit and have Neoplasm malignant?

- Check whether Neoplasm malignant is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ayvakit:

Ayvakit (7,362 reports)

Browse all side effects of Ayvakit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neoplasm malignant:

Neoplasm malignant (1,542 drugs)

Browse all the conditions that are associated with Neoplasm malignant:

Neoplasm malignant (1,261 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on avapritinib (the active ingredients of Ayvakit) and Ayvakit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.