Azathioprine and Hypocalcaemia - a phase IV clinical study of FDA data
Summary:
Hypocalcaemia is reported as a side effect among people who take Azathioprine (azathioprine sodium), especially for people who are female, 40-49 old, also take Prednisolone, and have Immunodeficiency disorders.
The phase IV clinical study analyzes which people have Hypocalcaemia when taking Azathioprine. It is created by eHealthMe based on reports of 59,932 people who have side effects when taking Azathioprine from the FDA, and is updated regularly.
What is Azathioprine?
Azathioprine has active ingredients of azathioprine sodium. It is often used in crohn's disease. eHealthMe is studying from 60,623 Azathioprine users. Check the latest studies of Azathioprine.
What is Hypocalcaemia?
Hypocalcaemia (levels of calcium in blood serum are abnormally low) is found to be associated with 1,193 drugs and 1,302 conditions by eHealthMe. Check the latest studies of Hypocalcaemia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
59,932 people reported to have side effects when taking Azathioprine.
Among them, 49 people (0.08%) have Hypocalcaemia.

Among these 49 people:
What is the gender of people who have Hypocalcaemia when taking Azathioprine? *
- female: 70 %
- male: 30 %
What is the age of people who have Hypocalcaemia when taking Azathioprine? *
- 0-1: 0.0 %
- 2-9: 2.86 %
- 10-19: 2.86 %
- 20-29: 8.57 %
- 30-39: 5.71 %
- 40-49: 45.71 %
- 50-59: 31.43 %
- 60+: 2.86 %
What are other drugs people take besides Azathioprine? *
- Prednisolone: 10 people, 20.41%
- Humira: 8 people, 16.33%
- Cyclosporine: 7 people, 14.29%
- Prednisone: 7 people, 14.29%
- Calcium: 4 people, 8.16%
- Pantoprazole: 4 people, 8.16%
- Tacrolimus: 4 people, 8.16%
- Methotrexate: 3 people, 6.12%
- Lovenox: 3 people, 6.12%
- Mesalamine: 3 people, 6.12%
What are other side effects people have besides Hypocalcaemia? *
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 10 people, 20.41%
- Fatigue (feeling of tiredness): 9 people, 18.37%
- Gait Disturbance: 9 people, 18.37%
- Diarrhea: 8 people, 16.33%
- Anaemia (lack of blood): 8 people, 16.33%
- Fever: 8 people, 16.33%
- Weakness: 7 people, 14.29%
- Hyperkalemia (damage to or disease of the kidney): 7 people, 14.29%
- Weight Decreased: 7 people, 14.29%
- Upper Respiratory Tract Infection: 7 people, 14.29%
What are the existing conditions these people have? *
- Immunodeficiency Disorders: 7 people, 14.29%
- Vitamin D Decreased: 3 people, 6.12%
- Blood Potassium Decreased: 3 people, 6.12%
- Gout (uric acid crystals building up in the body): 3 people, 6.12%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 6.12%
- Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 3 people, 6.12%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 6.12%
- Type 2 Diabetes: 3 people, 6.12%
- Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 2 people, 4.08%
- Polyarthritis (arthritis which involves 5 or more joints simultaneously): 2 people, 4.08%
* Approximation only. Some reports may have incomplete information.
Do you take Azathioprine and have Hypocalcaemia?
- Check whether Hypocalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Azathioprine:
- Azathioprine (60,623 reports)
Hypocalcaemia treatments and more:
- Hypocalcaemia (26,346 reports)
How severe was Hypocalcaemia and when was it recovered:
Expand to all the drugs that have ingredients of azathioprine sodium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azathioprine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypocalcaemia:
- Hypocalcaemia (1,193 drugs)
Browse all the conditions that are associated with Hypocalcaemia:
- Hypocalcaemia (1,302 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on azathioprine sodium (the active ingredients of Azathioprine) and Azathioprine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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