B6 and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take B6 (pyridoxine (vitamin b6)), especially for people who are male, 60+ old, also take Keppra, and have Hyperkalemia.

The phase IV clinical study analyzes which people have Stroke when taking B6. It is created by eHealthMe based on reports of 931 people who have side effects when taking B6 from the FDA, and is updated regularly.

What is B6?

B6 has active ingredients of pyridoxine (vitamin b6). eHealthMe is studying from 1,043 B6 users. Check the latest studies of B6.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,370 drugs and 3,012 conditions by eHealthMe. Check the latest studies of Stroke.

On Nov, 10, 2025

931 people reported to have side effects when taking B6.
Among them, 13 people (1.4%) have Stroke.

Among these 13 people:

What is the gender of people who have Stroke when taking B6? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Stroke when taking B6? *

What are other drugs people take besides B6? *

What are other side effects people have besides Stroke? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 53.85%
Blood Potassium Abnormal: 5 people, 38.46%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 38.46%
Dizziness: 4 people, 30.77%
Drug Ineffective: 4 people, 30.77%
Weakness: 4 people, 30.77%
Product Taste Abnormal: 4 people, 30.77%
Hyperkalemia (damage to or disease of the kidney): 4 people, 30.77%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 15.38%
Full Blood Count Decreased: 2 people, 15.38%

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 5 people, 38.46%
Thyroid Diseases: 4 people, 30.77%
Multiple Myeloma (cancer of the plasma cells): 4 people, 30.77%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 15.38%
Sleep Disorder: 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take B6 and have Stroke?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to B6:

B6 (1,043 reports)

Stroke treatments and more:

Stroke (334,632 reports)

Browse all side effects of B6:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,370 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,012 conditions)

Related publications that referenced our studies

Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .
Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine (vitamin b6) (the active ingredients of B6) and B6 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.