Bactrim and Exercise tolerance decreased - a phase IV clinical study of FDA data

Summary:

Exercise tolerance decreased is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Truvada, and have Hiv infection.

The phase IV clinical study analyzes which people have Exercise tolerance decreased when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Exercise tolerance decreased?

Exercise tolerance decreased is found to be associated with 625 drugs and 725 conditions by eHealthMe. Check the latest studies of Exercise tolerance decreased.

On Jul, 27, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 33 people (0.04%) have Exercise tolerance decreased.

Could Bactrim cause Exercise tolerance decreased?

Among these 33 people:

How long have people been on Bactrim when they have Exercise tolerance decreased? *

What is the gender of people who have Exercise tolerance decreased when taking Bactrim? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Exercise tolerance decreased when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Exercise tolerance decreased? *

Pain: 18 people, 54.55%
Fatigue (feeling of tiredness): 16 people, 48.48%
Stress And Anxiety: 16 people, 48.48%
Emotional Distress: 12 people, 36.36%
Bone Density Decreased: 11 people, 33.33%
Weakness: 10 people, 30.30%
Memory Loss: 9 people, 27.27%
Muscle Spasms (muscle contraction): 8 people, 24.24%
Weight Decreased: 8 people, 24.24%
Chronic Kidney Disease: 8 people, 24.24%

What are the existing conditions these people have? *

Hiv Infection: 10 people, 30.30%
High Blood Cholesterol: 5 people, 15.15%
Diabetes: 5 people, 15.15%
Human Seminal Plasma Hypersensitivity: 5 people, 15.15%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 5 people, 15.15%
Muscle Spasms (muscle contraction): 5 people, 15.15%
Hair Loss: 4 people, 12.12%
Stress And Anxiety: 3 people, 9.09%
Hot Flush (sudden feelings of heat): 2 people, 6.06%
Cardiac Disorder: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Exercise tolerance decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Exercise tolerance decreased treatments and more:

Exercise tolerance decreased (6,725 reports)

How severe was Exercise tolerance decreased and when was it recovered:

Exercise tolerance decreased in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Exercise tolerance decreased and drugs with ingredients of sulfamethoxazole; trimethoprim (85 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (625 drugs)

Browse all the conditions that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (725 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.