Bactrim and Injection site discharge - a phase IV clinical study of FDA data

Summary:

Injection site discharge is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are female, 60+ old, also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Injection site discharge when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Injection site discharge?

Injection site discharge is found to be associated with 185 drugs and 158 conditions by eHealthMe. Check the latest studies of Injection site discharge.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 18 people (0.02%) have Injection site discharge.

Could Bactrim cause Injection site discharge?

Among these 18 people:

What is the gender of people who have Injection site discharge when taking Bactrim? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Injection site discharge when taking Bactrim? *

What are other drugs people take besides Bactrim? *

Epinephrine: 14 people, 77.78%
Acetaminophen: 11 people, 61.11%
Sodium Chloride: 9 people, 50.00%
Lidocaine: 7 people, 38.89%
Mupirocin: 7 people, 38.89%
Nystatin: 6 people, 33.33%
Prednisone: 6 people, 33.33%
Fluticasone Propionate: 6 people, 33.33%
Azelastine Hydrochloride: 6 people, 33.33%
Pantoprazole Sodium: 5 people, 27.78%

What are other side effects people have besides Injection site discharge? *

Sinusitis (inflammation of sinus): 9 people, 50.00%
Infusion Site Pain: 7 people, 38.89%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 5 people, 27.78%
Tooth Fracture: 4 people, 22.22%
Tumor: 4 people, 22.22%
Precancerous Cells Present: 4 people, 22.22%
Gingival Pain (gum pain): 4 people, 22.22%
Nausea (feeling of having an urge to vomit): 4 people, 22.22%
Oxygen Saturation Decreased: 4 people, 22.22%
Heart Rate Decreased: 4 people, 22.22%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 44.44%
Primary Immunodeficiency Syndrome: 5 people, 27.78%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 4 people, 22.22%
Myositis (inflammation of the muscles): 3 people, 16.67%
Immune System Disorder: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Injection site discharge?

- Check whether Injection site discharge is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Injection site discharge treatments and more:

Injection site discharge (2,651 reports)

How severe was Injection site discharge and when was it recovered:

Injection site discharge in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Injection site discharge and drugs with ingredients of sulfamethoxazole; trimethoprim (5 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site discharge:

Injection site discharge (185 drugs)

Browse all the conditions that are associated with Injection site discharge:

Injection site discharge (158 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.