Bactrim and Tongue ulceration - a phase IV clinical study of FDA data

Summary:

Tongue ulceration is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Zithromax, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Tongue ulceration when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Tongue ulceration?

Tongue ulceration (ulcers on tongue) is found to be associated with 551 drugs and 597 conditions by eHealthMe. Check the latest studies of Tongue ulceration.

On Jul, 13, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 41 people (0.05%) have Tongue ulceration.

Among these 41 people:

How long have people been on Bactrim when they have Tongue ulceration? *

What is the gender of people who have Tongue ulceration when taking Bactrim? *

female: 43.24 %
male: 56.76 %

What is the age of people who have Tongue ulceration when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Tongue ulceration? *

Stress And Anxiety: 19 people, 46.34%
Upper Respiratory Tract Infection: 17 people, 41.46%
Nausea (feeling of having an urge to vomit): 16 people, 39.02%
Pain: 15 people, 36.59%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 14 people, 34.15%
Acute Kidney Failure: 14 people, 34.15%
Impaired Healing: 14 people, 34.15%
Erection Problems: 13 people, 31.71%
Mastication Disorder (disease of chewing food): 13 people, 31.71%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 13 people, 31.71%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 14 people, 34.15%
Cystic Fibrosis (disease of the secretary glands): 4 people, 9.76%
Type 2 Diabetes: 3 people, 7.32%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 7.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.32%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 7.32%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 7.32%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 7.32%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 4.88%
Glomerulonephritis Chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli): 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Tongue ulceration?

- Check whether Tongue ulceration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Tongue ulceration treatments and more:

Tongue ulceration (4,423 reports)

How severe was Tongue ulceration and when was it recovered:

Tongue ulceration in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Tongue ulceration and drugs with ingredients of sulfamethoxazole; trimethoprim (85 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tongue ulceration:

Tongue ulceration (551 drugs)

Browse all the conditions that are associated with Tongue ulceration:

Tongue ulceration (597 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.