Benadryl and Immobile - a phase IV clinical study of FDA data

Summary:

Immobile is reported as a side effect among people who take Benadryl (diphenhydramine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Solu-Medrol, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Immobile when taking Benadryl. It is created by eHealthMe based on reports of 100,139 people who have side effects when taking Benadryl from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.

What is Immobile?

Immobile (not moving) is found to be associated with 471 drugs and 582 conditions by eHealthMe. Check the latest studies of Immobile.

On Jul, 20, 2026

100,139 people reported to have side effects when taking Benadryl.
Among them, 48 people (0.05%) have Immobile.

Among these 48 people:

How long have people been on Benadryl when they have Immobile? *

What is the gender of people who have Immobile when taking Benadryl? *

female: 64.1 %
male: 35.9 %

What is the age of people who have Immobile when taking Benadryl? *

What are other drugs people take besides Benadryl? *

What are other side effects people have besides Immobile? *

Fatigue (feeling of tiredness): 17 people, 35.42%
Pain: 15 people, 31.25%
Nausea (feeling of having an urge to vomit): 15 people, 31.25%
Dizziness: 13 people, 27.08%
Nausea And Vomiting: 13 people, 27.08%
Weakness: 12 people, 25.00%
Urinary Tract Infection: 12 people, 25.00%
Fall: 11 people, 22.92%
Constipation: 10 people, 20.83%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 10 people, 20.83%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 14.58%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 8.33%
Delusion (a false belief or opinion): 3 people, 6.25%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 6.25%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 6.25%
High Blood Cholesterol: 3 people, 6.25%
Parkinson's Disease: 3 people, 6.25%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Benadryl and have Immobile?

- Check whether Immobile is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benadryl:

Benadryl (104,954 reports)

Immobile treatments and more:

Immobile (5,336 reports)

Browse all side effects of Benadryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Immobile:

Immobile (471 drugs)

Browse all the conditions that are associated with Immobile:

Immobile (582 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Benadryl) and Benadryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.