Benadryl and Systemic candida - a phase IV clinical study of FDA data

Summary:

Systemic candida is reported as a side effect among people who take Benadryl (diphenhydramine hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Ativan, and have Nausea.

The phase IV clinical study analyzes which people have Systemic candida when taking Benadryl. It is created by eHealthMe based on reports of 100,139 people who have side effects when taking Benadryl from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.

What is Systemic candida?

Systemic candida (whole body fungal infection) is found to be associated with 278 drugs and 409 conditions by eHealthMe. Check the latest studies of Systemic candida.

On Jul, 19, 2026

100,139 people reported to have side effects when taking Benadryl.
Among them, 13 people (0.01%) have Systemic candida.

Among these 13 people:

How long have people been on Benadryl when they have Systemic candida? *

What is the gender of people who have Systemic candida when taking Benadryl? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Systemic candida when taking Benadryl? *

What are other drugs people take besides Benadryl? *

What are other side effects people have besides Systemic candida? *

Fever: 9 people, 69.23%
Weakness: 7 people, 53.85%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 53.85%
Hypotension (abnormally low blood pressure): 7 people, 53.85%
Confusional State: 6 people, 46.15%
Thrombocytopenia (decrease of platelets in blood): 6 people, 46.15%
Pleural Effusion (water on the lungs): 6 people, 46.15%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 5 people, 38.46%
Ileus Paralytic (obstruction of the intestine due to paralysis of the intestinal muscles): 5 people, 38.46%
Pain In Extremity: 5 people, 38.46%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 53.85%
Respiratory Disorder (respiratory disease): 4 people, 30.77%
Anaesthesia: 4 people, 30.77%
Pain In Extremity: 3 people, 23.08%
Pain: 3 people, 23.08%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 23.08%
Fever: 2 people, 15.38%
Bone Marrow Conditioning Regimen: 2 people, 15.38%
Rosacea (a skin condition that causes facial redness): 1 person, 7.69%
Rashes (redness): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Benadryl and have Systemic candida?

- Check whether Systemic candida is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benadryl:

Benadryl (104,954 reports)

Browse all side effects of Benadryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic candida:

Systemic candida (278 drugs)

Browse all the conditions that are associated with Systemic candida:

Systemic candida (409 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Benadryl) and Benadryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.