Benadryl and Venous pressure jugular increased - a phase IV clinical study of FDA data

Summary:

Venous pressure jugular increased is reported as a side effect among people who take Benadryl (diphenhydramine hydrochloride), especially for people who are male, 50-59 old, also take Tylenol, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Venous pressure jugular increased when taking Benadryl. It is created by eHealthMe based on reports of 100,139 people who have side effects when taking Benadryl from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,955 Benadryl users. Check the latest studies of Benadryl.

What is Venous pressure jugular increased?

Venous pressure jugular increased is found to be associated with 92 drugs and 209 conditions by eHealthMe. Check the latest studies of Venous pressure jugular increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

100,139 people reported to have side effects when taking Benadryl.
Among them, 11 people (0.01%) have Venous pressure jugular increased.

Could Benadryl cause Venous pressure jugular increased?

Among these 11 people:

What is the gender of people who have Venous pressure jugular increased when taking Benadryl? *

female: 50 %
male: 50 %

What is the age of people who have Venous pressure jugular increased when taking Benadryl? *

What are other drugs people take besides Benadryl? *

Methylprednisolone Sodium Succinate: 7 people, 63.64%
Prednisone: 7 people, 63.64%
Calcium Carbonate: 7 people, 63.64%
Clobazam: 7 people, 63.64%
Epinephrine: 7 people, 63.64%
Naproxen: 7 people, 63.64%
Pantoprazole: 7 people, 63.64%
Actemra: 7 people, 63.64%
Ventolin: 7 people, 63.64%
Tylenol: 7 people, 63.64%

What are other side effects people have besides Venous pressure jugular increased? *

Dyspnea Exertional: 9 people, 81.82%
Chest Pain: 9 people, 81.82%
Rales (an abnormal respiratory sound characterized by fine crackles): 9 people, 81.82%
White Blood Cells Urine Positive: 7 people, 63.64%
Cough: 7 people, 63.64%
High Blood Pressure: 7 people, 63.64%
Hepatojugular Reflux (a venous reflux occurring in congestive heart failure): 7 people, 63.64%
Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin): 7 people, 63.64%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 7 people, 63.64%
Hepatic Steatosis (fatty liver disease): 7 people, 63.64%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 63.64%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Benadryl and have Venous pressure jugular increased?

- Check whether Venous pressure jugular increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benadryl:

Benadryl (104,955 reports)

Browse all side effects of Benadryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Venous pressure jugular increased:

Venous pressure jugular increased (92 drugs)

Browse all the conditions that are associated with Venous pressure jugular increased:

Venous pressure jugular increased (209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Benadryl) and Benadryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.