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Bendamustine and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Bendamustine (bendamustine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Adcetris, and have Hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Bendamustine. It is created by eHealthMe based on reports of 9,503 people who have side effects when taking Bendamustine from the FDA, and is updated regularly.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,939 drugs and 2,856 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Jul, 21, 2026

9,503 people reported to have side effects when taking Bendamustine.
Among them, 36 people (0.38%) have Anaphylaxis.

Could Bendamustine cause Anaphylaxis?

Among these 36 people:

How long have people been on Bendamustine when they have Anaphylaxis? *

  • < 1 month: 90.91 %
  • 1 - 6 months: 9.09 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anaphylaxis when taking Bendamustine? *

  • female: 32.26 %
  • male: 67.74 %

What is the age of people who have Anaphylaxis when taking Bendamustine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.7 %
  • 20-29: 3.7 %
  • 30-39: 7.41 %
  • 40-49: 14.81 %
  • 50-59: 22.22 %
  • 60+: 48.15 %

What are other drugs people take besides Bendamustine? *

  1. Adcetris: 17 people, 47.22%
  2. Rituxan: 4 people, 11.11%
  3. Ciclosporin: 3 people, 8.33%
  4. Methotrexate: 3 people, 8.33%
  5. Ondansetron: 3 people, 8.33%
  6. Platinol: 2 people, 5.56%
  7. Bactrim: 2 people, 5.56%
  8. Gazyva: 2 people, 5.56%
  9. Cytarabine: 2 people, 5.56%
  10. Ibrutinib: 2 people, 5.56%

What are other side effects people have besides Anaphylaxis? *

  1. Fever: 5 people, 13.89%
  2. Infection: 4 people, 11.11%
  3. Hypotension (abnormally low blood pressure): 4 people, 11.11%
  4. Septic Shock (shock due to blood infection): 4 people, 11.11%
  5. Malaise (a feeling of general discomfort or uneasiness): 4 people, 11.11%
  6. Chills (felling of cold): 4 people, 11.11%
  7. Pneumonia: 3 people, 8.33%
  8. Inflammatory Marker Increased: 3 people, 8.33%
  9. Febrile Neutropenia (fever with reduced white blood cells): 3 people, 8.33%
  10. Loss Of Consciousness: 3 people, 8.33%

What are the existing conditions these people have? *

  1. Hodgkin's Lymphoma (cancer originating from white blood cells): 15 people, 41.67%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 19.44%
  3. Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 8.33%
  4. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 2 people, 5.56%
  5. Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 1 person, 2.78%
  6. Nausea (feeling of having an urge to vomit): 1 person, 2.78%
  7. Mantle Cell Lymphoma Recurrent (cancer of lymphocytes, a type of white blood cell- recurrent): 1 person, 2.78%
  8. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 2.78%
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 2.78%
  10. Extranodal Marginal Zone B-Cell Lymphoma (Malt Type) (cancer originating from b cells in the marginal zone of the malt): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Bendamustine and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bendamustine:

Anaphylaxis treatments and more:

How severe was Anaphylaxis and when was it recovered:

Expand to all the drugs that have ingredients of bendamustine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Browse all the conditions that are associated with Anaphylaxis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on bendamustine (the active ingredients of Bendamustine) and Bendamustine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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