Bendamustine and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Bendamustine (bendamustine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Bendamustine. It is created by eHealthMe based on reports of 9,503 people who have side effects when taking Bendamustine from the FDA, and is updated regularly.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,466 drugs and 2,016 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Dec, 05, 2025

9,503 people reported to have side effects when taking Bendamustine.
Among them, 26 people (0.27%) have Hepatic function abnormal.

Could Bendamustine cause Hepatic function abnormal?

Among these 26 people:

How long have people been on Bendamustine when they have Hepatic function abnormal? *

What is the gender of people who have Hepatic function abnormal when taking Bendamustine? *

female: 21.74 %
male: 78.26 %

What is the age of people who have Hepatic function abnormal when taking Bendamustine? *

What are other drugs people take besides Bendamustine? *

Cyclophosphamide: 13 people, 50.00%
Prednisone: 13 people, 50.00%
Carboplatin: 12 people, 46.15%
Etoposide: 12 people, 46.15%
Ifosfamide: 10 people, 38.46%
Oxaliplatin: 8 people, 30.77%
Gemcitabine: 7 people, 26.92%
Lenalidomide: 5 people, 19.23%
Mitoxantrone: 3 people, 11.54%
Doxorubicin Hydrochloride: 3 people, 11.54%

What are other side effects people have besides Hepatic function abnormal? *

Blood Lactate Dehydrogenase Increased: 11 people, 42.31%
Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 9 people, 34.62%
Fungal Infection: 9 people, 34.62%
Thrombocytopenia (decrease of platelets in blood): 6 people, 23.08%
Pneumonia: 5 people, 19.23%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 15.38%
Leukopenia (less number of white blood cells in blood): 4 people, 15.38%
Weakness: 4 people, 15.38%
Anaemia (lack of blood): 4 people, 15.38%
Renal Impairment (severely reduced kidney function): 4 people, 15.38%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 16 people, 61.54%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 11.54%
Extranodal Marginal Zone B-Cell Lymphoma (Malt Type) (cancer originating from b cells in the marginal zone of the malt): 2 people, 7.69%
Diffuse Large B-Cell Lymphoma Stage Ii (cancer of b cells, a type of white blood cell-stage ii): 2 people, 7.69%
B-Cell Lymphoma Refractory (blood cancer affecting b cells-relapsed): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Bendamustine and have Hepatic function abnormal?

- Check whether Hepatic function abnormal is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bendamustine:

Bendamustine (9,508 reports)

Browse all side effects of Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,466 drugs)

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,016 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bendamustine (the active ingredients of Bendamustine) and Bendamustine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.