Benicar and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Benicar (olmesartan medoxomil), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Lasix, and have Paget's disease.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Benicar. It is created by eHealthMe based on reports of 34,073 people who have side effects when taking Benicar from the FDA, and is updated regularly.

What is Benicar?

Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,164 drugs and 841 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.



On Mar, 28, 2026

34,073 people reported to have side effects when taking Benicar.
Among them, 26 people (0.08%) have Sinus node dysfunction.

Could Benicar cause Sinus node dysfunction?

Among these 26 people:

How long have people been on Benicar when they have Sinus node dysfunction? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 60 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus node dysfunction when taking Benicar? *

  • female: 72.73 %
  • male: 27.27 %

What is the age of people who have Sinus node dysfunction when taking Benicar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 5 %
  • 60+: 95 %

What are other drugs people take besides Benicar? *

  1. Lasix: 14 people, 53.85%
  2. Digoxin: 13 people, 50.00%
  3. Protonix: 11 people, 42.31%
  4. Plavix: 10 people, 38.46%
  5. Prilosec: 10 people, 38.46%
  6. Hydrochlorothiazide: 10 people, 38.46%
  7. Clonidine: 10 people, 38.46%
  8. Colace: 10 people, 38.46%
  9. Synthroid: 10 people, 38.46%
  10. Flagyl: 9 people, 34.62%

What are other side effects people have besides Sinus node dysfunction? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 18 people, 69.23%
  2. Hypotension (abnormally low blood pressure): 16 people, 61.54%
  3. Joint Pain: 14 people, 53.85%
  4. Pneumonia: 13 people, 50.00%
  5. Stress And Anxiety: 13 people, 50.00%
  6. Anaemia (lack of blood): 13 people, 50.00%
  7. Tricuspid Valve Incompetence (inefficient heart valve): 12 people, 46.15%
  8. Heart Attack: 12 people, 46.15%
  9. Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 12 people, 46.15%
  10. Pain: 12 people, 46.15%

What are the existing conditions these people have? *

  1. Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 9 people, 34.62%
  2. Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 19.23%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 15.38%
  4. Diabetes: 2 people, 7.69%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 3.85%
  6. Prostate Cancer Metastatic: 1 person, 3.85%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 3.85%
  8. Pain: 1 person, 3.85%
  9. High Blood Cholesterol: 1 person, 3.85%
  10. Breast Cancer Metastatic: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Benicar and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benicar:

Sinus node dysfunction treatments and more:

How severe was Sinus node dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of olmesartan medoxomil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Benicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Browse all the conditions that are associated with Sinus node dysfunction:


How the study uses the data?

The study uses data from the FDA. It is based on olmesartan medoxomil (the active ingredients of Benicar) and Benicar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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