Bextra and Sleeping difficulty - a phase IV clinical study of FDA data
Summary:
Sleeping difficulty is reported as a side effect among people who take Bextra (valdecoxib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Celebrex, and have Arthritis.
The phase IV clinical study analyzes which people have Sleeping difficulty when taking Bextra. It is created by eHealthMe based on reports of 20,982 people who have side effects when taking Bextra from the FDA, and is updated regularly.
What is Bextra?
Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.
What is Sleeping difficulty?
Sleeping difficulty (difficult sleeping) is found to be associated with 4,219 drugs and 5,350 conditions by eHealthMe. Check the latest studies of Sleeping difficulty.
20,982 people reported to have side effects when taking Bextra.
Among them, 524 people (2.5%) have Sleeping difficulty.

Among these 524 people:
How long have people been on Bextra when they have Sleeping difficulty? *
- < 1 month: 60.47 %
- 1 - 6 months: 13.95 %
- 6 - 12 months: 3.49 %
- 1 - 2 years: 10.47 %
- 2 - 5 years: 11.63 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Sleeping difficulty when taking Bextra? *
- female: 71.29 %
- male: 28.71 %
What is the age of people who have Sleeping difficulty when taking Bextra? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 1.72 %
- 20-29: 2.94 %
- 30-39: 6.86 %
- 40-49: 20.1 %
- 50-59: 30.15 %
- 60+: 38.24 %
What are other drugs people take besides Bextra? *
- Celebrex: 136 people, 25.95%
- Neurontin: 97 people, 18.51%
- Zometa: 96 people, 18.32%
- Vioxx: 94 people, 17.94%
- Vicodin: 92 people, 17.56%
- Oxycontin: 89 people, 16.98%
- Ambien: 87 people, 16.60%
- Prilosec: 80 people, 15.27%
- Xanax: 70 people, 13.36%
- Lasix: 69 people, 13.17%
What are other side effects people have besides Sleeping difficulty? *
- Stress And Anxiety: 200 people, 38.17%
- Depression: 180 people, 34.35%
- Nausea (feeling of having an urge to vomit): 157 people, 29.96%
- Joint Pain: 152 people, 29.01%
- Back Pain: 126 people, 24.05%
- Chest Pain: 126 people, 24.05%
- Dyspnea (difficult or laboured breathing): 119 people, 22.71%
- Fatigue (feeling of tiredness): 118 people, 22.52%
- Pain In Extremity: 115 people, 21.95%
- Headache (pain in head): 115 people, 21.95%
What are the existing conditions these people have? *
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 62 people, 11.83%
- Depression: 45 people, 8.59%
- Osteoporosis (bones weak and more likely to break): 34 people, 6.49%
- Ill-Defined Disorder: 34 people, 6.49%
- Sleep Disorder: 23 people, 4.39%
- Joint Pain: 22 people, 4.20%
- High Blood Pressure: 18 people, 3.44%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 17 people, 3.24%
- Muscle Spasms (muscle contraction): 16 people, 3.05%
- Bone Density Abnormal: 16 people, 3.05%
* Approximation only. Some reports may have incomplete information.
Do you take Bextra and have Sleeping difficulty?
- Check whether Sleeping difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Bextra:
- Bextra (20,994 reports)
Sleeping difficulty treatments and more:
- Sleeping difficulty (437,992 reports)
How severe was Sleeping difficulty and when was it recovered:
Expand to all the drugs that have ingredients of valdecoxib:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Bextra side effects:
- Bextra side effect: Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) (3,565 reports)
- Bextra side effect: Depression (1,160 reports)
Browse all side effects of Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Sleeping difficulty:
- Prednisone side effect: Sleeping difficulty (14,705 reports)
- Aspirin side effect: Sleeping difficulty (12,915 reports)
- Lyrica side effect: Sleeping difficulty (11,256 reports)
- Cymbalta side effect: Sleeping difficulty (10,012 reports)
- Methotrexate side effect: Sleeping difficulty (9,775 reports)
- Humira side effect: Sleeping difficulty (9,315 reports)
- Vitamin d side effect: Sleeping difficulty (8,911 reports)
- Gabapentin side effect: Sleeping difficulty (8,758 reports)
- Omeprazole side effect: Sleeping difficulty (8,666 reports)
- Synthroid side effect: Sleeping difficulty (8,339 reports)
Browse all the drugs that are associated with Sleeping difficulty:
- Sleeping difficulty (4,219 drugs)
Common conditions associated with Sleeping difficulty:
- Depression aggravated: 17,540 reports
- Antidepressant therapy: 17,500 reports
- Pain exacerbated: 13,668 reports
- Ra: 13,625 reports
- Pain relief: 13,485 reports
- Ms: 12,998 reports
- Hypertension: 12,107 reports
- Hbp: 12,061 reports
- Anxiety aggravated: 10,449 reports
- Tension: 10,431 reports
Browse all the conditions that are associated with Sleeping difficulty:
- Sleeping difficulty (5,350 conditions)
Drugs similar to Bextra and Sleeping difficulty :
- Acetaminophen side effect: Sleeping difficulty
- Advil side effect: Sleeping difficulty
- Aleve side effect: Sleeping difficulty
- Amitriptyline hydrochloride side effect: Sleeping difficulty
- Aspirin side effect: Sleeping difficulty
- Celebrex side effect: Sleeping difficulty
- Codeine side effect: Sleeping difficulty
- Cymbalta side effect: Sleeping difficulty
- Darvocet side effect: Sleeping difficulty
- Darvocet-n 100 side effect: Sleeping difficulty
- Dilaudid side effect: Sleeping difficulty
- Flexeril side effect: Sleeping difficulty
- Gabapentin side effect: Sleeping difficulty
- Hydrocodone bitartrate and acetaminophen side effect: Sleeping difficulty
- Hydromorphone hydrochloride side effect: Sleeping difficulty
- Ibu side effect: Sleeping difficulty
- Ibuprofen side effect: Sleeping difficulty
- Lortab side effect: Sleeping difficulty
- Lyrica side effect: Sleeping difficulty
- Meloxicam side effect: Sleeping difficulty
- Methadone hydrochloride side effect: Sleeping difficulty
- Morphine side effect: Sleeping difficulty
- Morphine sulfate side effect: Sleeping difficulty
- Motrin side effect: Sleeping difficulty
- Naproxen side effect: Sleeping difficulty
- Neurontin side effect: Sleeping difficulty
- Norco side effect: Sleeping difficulty
- Oxycodone side effect: Sleeping difficulty
- Oxycodone and acetaminophen side effect: Sleeping difficulty
- Oxycodone hydrochloride side effect: Sleeping difficulty
- Oxycontin side effect: Sleeping difficulty
- Paracetamol side effect: Sleeping difficulty
- Percocet side effect: Sleeping difficulty
- Profen side effect: Sleeping difficulty
- Suboxone side effect: Sleeping difficulty
- Tramadol side effect: Sleeping difficulty
- Tramadol hydrochloride side effect: Sleeping difficulty
- Tylenol side effect: Sleeping difficulty
- Tylenol w/ codeine side effect: Sleeping difficulty
- Tylenol w/ codeine no. 3 side effect: Sleeping difficulty
- Ultram side effect: Sleeping difficulty
- Vicodin side effect: Sleeping difficulty
- Vicodin es side effect: Sleeping difficulty
How the study uses the data?
The study uses data from the FDA. It is based on valdecoxib (the active ingredients of Bextra) and Bextra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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