Bicnu and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Bicnu (carmustine), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Etoposide, and have Mantle cell lymphoma stage iii.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Bicnu. It is created by eHealthMe based on reports of 1,133 people who have side effects when taking Bicnu from the FDA, and is updated regularly.

What is Bicnu?

Bicnu has active ingredients of carmustine. eHealthMe is studying from 1,135 Bicnu users. Check the latest studies of Bicnu.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,493 conditions by eHealthMe. Check the latest studies of Acute kidney failure.



On Jul, 18, 2026

1,133 people reported to have side effects when taking Bicnu.
Among them, 24 people (2.12%) have Acute kidney failure.

Could Bicnu cause Acute kidney failure?

Among these 24 people:

How long have people been on Bicnu when they have Acute kidney failure? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Acute kidney failure when taking Bicnu? *

  • female: 30.43 %
  • male: 69.57 %

What is the age of people who have Acute kidney failure when taking Bicnu? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.17 %
  • 40-49: 4.17 %
  • 50-59: 50.0 %
  • 60+: 41.67 %

What are other drugs people take besides Bicnu? *

  1. Etoposide: 12 people, 50.00%
  2. Piperacillin And Tazobactam: 8 people, 33.33%
  3. Alkeran: 6 people, 25.00%
  4. Fluconazole: 6 people, 25.00%
  5. Melphalan: 6 people, 25.00%
  6. Cytarabine: 6 people, 25.00%
  7. Dexamethasone: 5 people, 20.83%
  8. Oxaliplatin: 3 people, 12.50%
  9. Lasix: 3 people, 12.50%
  10. Ifosfamide: 3 people, 12.50%

What are other side effects people have besides Acute kidney failure? *

  1. Fever: 8 people, 33.33%
  2. Hepatic Failure (liver failure): 7 people, 29.17%
  3. Weight Increased: 6 people, 25.00%
  4. Venoocclusive Liver Disease (small veins in the liver are obstructed): 6 people, 25.00%
  5. Anuria (failure of the kidneys to produce urine): 6 people, 25.00%
  6. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 6 people, 25.00%
  7. Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function): 6 people, 25.00%
  8. Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 6 people, 25.00%
  9. Lactic Acidosis (low ph in body tissues): 5 people, 20.83%
  10. Arrhythmias (irregular heartbeat): 5 people, 20.83%

What are the existing conditions these people have? *

  1. Mantle Cell Lymphoma Stage Iii (cancer of lymphocytes, a type of white blood cell- stage iii): 5 people, 20.83%
  2. Lung Disorder (lung disease): 2 people, 8.33%
  3. Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 2 people, 8.33%
  4. Cardiac Failure: 2 people, 8.33%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 4.17%
  6. Nausea (feeling of having an urge to vomit): 1 person, 4.17%
  7. Multiple Myeloma (cancer of the plasma cells): 1 person, 4.17%
  8. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 4.17%
  9. Malignant Lymphoid Neoplasm (malignant growth or tumour caused by abnormal and uncontrolled cell division in lymph node): 1 person, 4.17%
  10. Indigestion: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Bicnu and have Acute kidney failure?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bicnu:

Acute kidney failure treatments and more:

How severe was Acute kidney failure and when was it recovered:

Expand to all the drugs that have ingredients of carmustine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bicnu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Browse all the conditions that are associated with Acute kidney failure:


How the study uses the data?

The study uses data from the FDA. It is based on carmustine (the active ingredients of Bicnu) and Bicnu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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