Boniva and Osteomalacia - a phase IV clinical study of FDA data

Summary:

Osteomalacia is reported as a side effect among people who take Boniva (ibandronate sodium), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Fosamax, and have Senile osteoporosis.

The phase IV clinical study analyzes which people have Osteomalacia when taking Boniva. It is created by eHealthMe based on reports of 26,949 people who have side effects when taking Boniva from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Osteomalacia?

Osteomalacia (softening of the bones due to a lack of vitamin d) is found to be associated with 240 drugs and 282 conditions by eHealthMe. Check the latest studies of Osteomalacia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

26,949 people reported to have side effects when taking Boniva.
Among them, 40 people (0.15%) have Osteomalacia.

Among these 40 people:

How long have people been on Boniva when they have Osteomalacia? *

What is the gender of people who have Osteomalacia when taking Boniva? *

female: 100 %
male: 0.0 %

What is the age of people who have Osteomalacia when taking Boniva? *

What are other drugs people take besides Boniva? *

Fosamax: 34 people, 85.00%
Premarin: 11 people, 27.50%
Vitamins: 7 people, 17.50%
Actonel: 6 people, 15.00%
Ambien: 5 people, 12.50%
Primidone: 4 people, 10.00%
Fluvoxamine Maleate: 4 people, 10.00%
Humira: 4 people, 10.00%
Hydroxychloroquine Sulfate: 4 people, 10.00%
Kadian: 4 people, 10.00%

What are other side effects people have besides Osteomalacia? *

Femur Fracture: 35 people, 87.50%
Fall: 23 people, 57.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 21 people, 52.50%
Broken Bone: 21 people, 52.50%
Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone): 18 people, 45.00%
Urinary Tract Infection: 18 people, 45.00%
Joint Pain: 17 people, 42.50%
Impaired Healing: 17 people, 42.50%
Stress And Anxiety: 17 people, 42.50%
Nausea (feeling of having an urge to vomit): 16 people, 40.00%

What are the existing conditions these people have? *

Senile Osteoporosis (weak bones with ageing): 7 people, 17.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 10.00%
Bone Density Decreased: 4 people, 10.00%
Pain: 4 people, 10.00%
Insomnia (sleeplessness): 4 people, 10.00%
Irritable Bowel Syndrome: 2 people, 5.00%
Depression: 2 people, 5.00%
Gastric Disorder (disease of stomach): 2 people, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and have Osteomalacia?

- Check whether Osteomalacia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Boniva:

Boniva (27,340 reports)

Osteomalacia treatments and more:

Osteomalacia (2,676 reports)

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteomalacia:

Osteomalacia (240 drugs)

Browse all the conditions that are associated with Osteomalacia:

Osteomalacia (282 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium (the active ingredients of Boniva) and Boniva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.