Bosentan and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Bosentan (bosentan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Opsumit, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Bosentan. It is created by eHealthMe based on reports of 10,925 people who have side effects when taking Bosentan from the FDA, and is updated regularly.

What is Bosentan?

Bosentan has active ingredients of bosentan. eHealthMe is studying from 10,925 Bosentan users. Check the latest studies of Bosentan.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,440 drugs and 2,021 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Jul, 20, 2026

10,925 people reported to have side effects when taking Bosentan.
Among them, 69 people (0.63%) have Hepatic function abnormal.

Could Bosentan cause Hepatic function abnormal?

Among these 69 people:

How long have people been on Bosentan when they have Hepatic function abnormal? *

What is the gender of people who have Hepatic function abnormal when taking Bosentan? *

female: 83.78 %
male: 16.22 %

What is the age of people who have Hepatic function abnormal when taking Bosentan? *

What are other drugs people take besides Bosentan? *

What are other side effects people have besides Hepatic function abnormal? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 10.14%
Aspartate Aminotransferase Increased: 7 people, 10.14%
Alanine Aminotransferase Increased: 7 people, 10.14%
Gamma-Glutamyltransferase Increased: 5 people, 7.25%
Death: 4 people, 5.80%
Dyspnea (difficult or laboured breathing): 4 people, 5.80%
Abdominal Distension: 3 people, 4.35%
Cardiac Failure: 3 people, 4.35%
Renal Impairment (severely reduced kidney function): 3 people, 4.35%
Nausea (feeling of having an urge to vomit): 3 people, 4.35%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 34 people, 49.28%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 10.14%
Stable Angina (a constant chest pain): 4 people, 5.80%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.80%
High Blood Pressure: 3 people, 4.35%
Skin Ulcer: 3 people, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 2.90%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 2.90%
Cardiac Failure: 2 people, 2.90%
Cellulitis (infection under the skin): 2 people, 2.90%

* Approximation only. Some reports may have incomplete information.

Do you take Bosentan and have Hepatic function abnormal?

- Check whether Hepatic function abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bosentan:

Bosentan (10,925 reports)

Browse all side effects of Bosentan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,441 drugs)

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,021 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bosentan (the active ingredients of Bosentan) and Bosentan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.