Botox and Attention deficit hyperactivity disorder - a phase IV clinical study of FDA data

Summary:

Attention deficit hyperactivity disorder is reported as a side effect among people who take Botox (botulinum toxin type a), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Amoxicillin, and have Headache.

The phase IV clinical study analyzes which people have Attention deficit hyperactivity disorder when taking Botox. It is created by eHealthMe based on reports of 69,984 people who have side effects when taking Botox from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Attention deficit hyperactivity disorder?

Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness) is found to be associated with 610 drugs and 1,393 conditions by eHealthMe. Check the latest studies of Attention deficit hyperactivity disorder.

On May, 06, 2026

69,984 people reported to have side effects when taking Botox.
Among them, 20 people (0.03%) have Attention deficit hyperactivity disorder.

Could Botox cause Attention deficit hyperactivity disorder?

Among these 20 people:

How long have people been on Botox when they have Attention deficit hyperactivity disorder? *

What is the gender of people who have Attention deficit hyperactivity disorder when taking Botox? *

female: 90 %
male: 10 %

What is the age of people who have Attention deficit hyperactivity disorder when taking Botox? *

What are other drugs people take besides Botox? *

What are other side effects people have besides Attention deficit hyperactivity disorder? *

Fatigue (feeling of tiredness): 10 people, 50.00%
Weight Decreased: 10 people, 50.00%
Memory Loss: 10 people, 50.00%
Vision Blurred: 10 people, 50.00%
Insomnia (sleeplessness): 10 people, 50.00%
Headache (pain in head): 10 people, 50.00%
Menstrual Disorder (disease of menstrual cycle): 10 people, 50.00%
Weakness: 9 people, 45.00%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 45.00%
Depression: 9 people, 45.00%

What are the existing conditions these people have? *

Headache (pain in head): 10 people, 50.00%
Birth Control: 7 people, 35.00%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 7 people, 35.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 15.00%
Stress And Anxiety: 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Skin Wrinkling (wrinkle on skin): 2 people, 10.00%
Muscle Tightness: 2 people, 10.00%
Central Nervous System Inflammation (infection of brain or spinal cord): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Botox and have Attention deficit hyperactivity disorder?

- Check whether Attention deficit hyperactivity disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Botox:

Botox (70,513 reports)

Attention deficit hyperactivity disorder treatments and more:

Attention deficit hyperactivity disorder (120,330 reports)

How severe was Attention deficit hyperactivity disorder and when was it recovered:

Attention deficit hyperactivity disorder in Botox

Expand to all the drugs that have ingredients of botulinum toxin type a:

Attention deficit hyperactivity disorder and drugs with ingredients of botulinum toxin type a (21 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Attention deficit hyperactivity disorder:

Attention deficit hyperactivity disorder (610 drugs)

Browse all the conditions that are associated with Attention deficit hyperactivity disorder:

Attention deficit hyperactivity disorder (1,393 conditions)

Related publications that referenced our studies

Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on botulinum toxin type a (the active ingredients of Botox) and Botox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.