Brexpiprazole and Hyperprolactinaemia - a phase IV clinical study of FDA data

Summary:

Hyperprolactinaemia is reported as a side effect among people who take Brexpiprazole (brexpiprazole), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Olanzapine, and have Schizophrenia.

The phase IV clinical study analyzes which people have Hyperprolactinaemia when taking Brexpiprazole. It is created by eHealthMe based on reports of 1,162 people who have side effects when taking Brexpiprazole from the FDA, and is updated regularly.

What is Brexpiprazole?

Brexpiprazole has active ingredients of brexpiprazole. eHealthMe is studying from 1,164 Brexpiprazole users. Check the latest studies of Brexpiprazole.

What is Hyperprolactinaemia?

Hyperprolactinaemia (abnormally high levels of prolactin in the blood) is found to be associated with 212 drugs and 392 conditions by eHealthMe. Check the latest studies of Hyperprolactinaemia.

On Aug, 04, 2026

1,162 people reported to have side effects when taking Brexpiprazole.
Among them, 21 people (1.81%) have Hyperprolactinaemia.

Could Brexpiprazole cause Hyperprolactinaemia?

Among these 21 people:

How long have people been on Brexpiprazole when they have Hyperprolactinaemia? *

What is the gender of people who have Hyperprolactinaemia when taking Brexpiprazole? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Hyperprolactinaemia when taking Brexpiprazole? *

What are other drugs people take besides Brexpiprazole? *

Olanzapine: 19 people, 90.48%
Aripiprazole: 18 people, 85.71%
Haloperidol: 16 people, 76.19%
Risperidone: 16 people, 76.19%
Clozapine: 15 people, 71.43%
Paliperidone: 11 people, 52.38%
Paliperidone Palmitate: 6 people, 28.57%
Risperdal Consta: 5 people, 23.81%
Rexulti: 3 people, 14.29%
Valproate Sodium: 2 people, 9.52%

What are other side effects people have besides Hyperprolactinaemia? *

Hypotension (abnormally low blood pressure): 17 people, 80.95%
Tremor (trembling or shaking movements in one or more parts of your body): 15 people, 71.43%
Insomnia (sleeplessness): 14 people, 66.67%
Fatigue (feeling of tiredness): 14 people, 66.67%
Weight Increased: 13 people, 61.90%
Depression: 13 people, 61.90%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 12 people, 57.14%
Stress And Anxiety: 12 people, 57.14%
Sedation: 8 people, 38.10%
Overdose: 8 people, 38.10%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 18 people, 85.71%
Psychotic Disorder: 1 person, 4.76%
Adverse Event: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Brexpiprazole and have Hyperprolactinaemia?

- Check whether Hyperprolactinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brexpiprazole:

Brexpiprazole (1,164 reports)

Browse all side effects of Brexpiprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperprolactinaemia:

Hyperprolactinaemia (212 drugs)

Browse all the conditions that are associated with Hyperprolactinaemia:

Hyperprolactinaemia (392 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brexpiprazole (the active ingredients of Brexpiprazole) and Brexpiprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.