Brintellix and Extrapyramidal disorder - a phase IV clinical study of FDA data

Summary:

Extrapyramidal disorder is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are male, 60+ old, also take Alphagan P, and have Major depression.

The phase IV clinical study analyzes which people have Extrapyramidal disorder when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Extrapyramidal disorder?

Extrapyramidal disorder (involuntary muscle spasms in the face and neck) is found to be associated with 814 drugs and 960 conditions by eHealthMe. Check the latest studies of Extrapyramidal disorder.

On Jul, 16, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 14 people (0.21%) have Extrapyramidal disorder.

Could Brintellix cause Extrapyramidal disorder?

Among these 14 people:

What is the gender of people who have Extrapyramidal disorder when taking Brintellix? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Extrapyramidal disorder when taking Brintellix? *

What are other drugs people take besides Brintellix? *

What are other side effects people have besides Extrapyramidal disorder? *

Fall: 4 people, 28.57%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 2 people, 14.29%
Pain: 2 people, 14.29%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 14.29%
Hypoaesthesia (reduced sense of touch or sensation): 2 people, 14.29%
Weakness: 1 person, 7.14%
Fever: 1 person, 7.14%
Confusional State: 1 person, 7.14%
Delusional Disorder, Unspecified Type: 1 person, 7.14%
Drowsiness: 1 person, 7.14%

What are the existing conditions these people have? *

Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 21.43%
Stress And Anxiety: 2 people, 14.29%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 14.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Extrapyramidal disorder?

- Check whether Extrapyramidal disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,748 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (814 drugs)

Browse all the conditions that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (960 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.