Bupivacaine and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Bupivacaine (bupivacaine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Morphine, and have Pain.

The phase IV clinical study analyzes which people have Chills when taking Bupivacaine. It is created by eHealthMe based on reports of 14,005 people who have side effects when taking Bupivacaine from the FDA, and is updated regularly.

What is Bupivacaine?

Bupivacaine has active ingredients of bupivacaine hydrochloride. eHealthMe is studying from 14,046 Bupivacaine users. Check the latest studies of Bupivacaine.

What is Chills?

Chills (felling of cold) is found to be associated with 2,549 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

14,005 people reported to have side effects when taking Bupivacaine.
Among them, 88 people (0.63%) have Chills.

Among these 88 people:

How long have people been on Bupivacaine when they have Chills? *

What is the gender of people who have Chills when taking Bupivacaine? *

female: 70.24 %
male: 29.76 %

What is the age of people who have Chills when taking Bupivacaine? *

What are other drugs people take besides Bupivacaine? *

What are other side effects people have besides Chills? *

Nausea (feeling of having an urge to vomit): 36 people, 40.91%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 29 people, 32.95%
Pain: 28 people, 31.82%
Hyperhidrosis (abnormally increased sweating): 21 people, 23.86%
Nausea And Vomiting: 20 people, 22.73%
Stress And Anxiety: 17 people, 19.32%
Weakness: 17 people, 19.32%
Dizziness: 13 people, 14.77%
Tremor (trembling or shaking movements in one or more parts of your body): 13 people, 14.77%
Itching: 13 people, 14.77%

What are the existing conditions these people have? *

Pain: 26 people, 29.55%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 7.95%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 7.95%
Back Pain: 6 people, 6.82%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 4 people, 4.55%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 4 people, 4.55%
High Blood Pressure: 4 people, 4.55%
Spinal Pain (pain in spine): 3 people, 3.41%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 3.41%
Respiratory Depression (respiration has a rate below 12 breaths): 3 people, 3.41%

* Approximation only. Some reports may have incomplete information.

Do you take Bupivacaine and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bupivacaine:

Bupivacaine (14,046 reports)

Chills treatments and more:

Chills (145,628 reports)

Browse all side effects of Bupivacaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Chills (2,549 drugs)

Browse all the conditions that are associated with Chills:

Chills (3,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupivacaine hydrochloride (the active ingredients of Bupivacaine) and Bupivacaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.