Buprenorphine and Delirium - a phase IV clinical study of FDA data

Summary:

Delirium is reported as a side effect among people who take Buprenorphine (buprenorphine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tiotropium Bromide, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Delirium when taking Buprenorphine. It is created by eHealthMe based on reports of 8,918 people who have side effects when taking Buprenorphine from the FDA, and is updated regularly.

What is Buprenorphine?

Buprenorphine has active ingredients of buprenorphine. It is often used in opioid intoxication. eHealthMe is studying from 9,053 Buprenorphine users. Check the latest studies of Buprenorphine.

What is Delirium?

Delirium (wild excitement) is found to be associated with 1,466 drugs and 2,976 conditions by eHealthMe. Check the latest studies of Delirium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

8,918 people reported to have side effects when taking Buprenorphine.
Among them, 67 people (0.75%) have Delirium.

Among these 67 people:

How long have people been on Buprenorphine when they have Delirium? *

What is the gender of people who have Delirium when taking Buprenorphine? *

female: 23.53 %
male: 76.47 %

What is the age of people who have Delirium when taking Buprenorphine? *

What are other drugs people take besides Buprenorphine? *

What are other side effects people have besides Delirium? *

Sedation: 26 people, 38.81%
Fall: 25 people, 37.31%
Rib Fracture: 24 people, 35.82%
Muscle Rigidity (muscle stiffness): 24 people, 35.82%
Sarcopenia (loss of muscle mass and strength): 23 people, 34.33%
Tardive Dyskinesia (a disorder that involves involuntary movements): 22 people, 32.84%
Mastication Disorder (disease of chewing food): 22 people, 32.84%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 22 people, 32.84%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 22 people, 32.84%
Swallowing Difficulty: 22 people, 32.84%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 13 people, 19.40%
Cancer Pain: 10 people, 14.93%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 14.93%
Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 10 people, 14.93%
Cardiac Failure: 6 people, 8.96%
Alcoholism (problems with alcohol): 4 people, 5.97%
Back Pain: 4 people, 5.97%
Pain: 4 people, 5.97%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 4.48%
Drug Dependence: 3 people, 4.48%

* Approximation only. Some reports may have incomplete information.

Do you take Buprenorphine and have Delirium?

- Check whether Delirium is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buprenorphine:

Buprenorphine (9,053 reports)

Delirium treatments and more:

Delirium (42,503 reports)

Browse all side effects of Buprenorphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Delirium:

Delirium (1,466 drugs)

Browse all the conditions that are associated with Delirium:

Delirium (2,976 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine (the active ingredients of Buprenorphine) and Buprenorphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.