Buscopan and Hypomagnesaemia - a phase IV clinical study of FDA data

Summary:

Hypomagnesaemia is reported as a side effect among people who take Buscopan (hyoscine butylbromide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypomagnesaemia when taking Buscopan. It is created by eHealthMe based on reports of 4,690 people who have side effects when taking Buscopan from the FDA, and is updated regularly.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

What is Hypomagnesaemia?

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood) is found to be associated with 1,027 drugs and 1,056 conditions by eHealthMe. Check the latest studies of Hypomagnesaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

4,690 people reported to have side effects when taking Buscopan.
Among them, 23 people (0.49%) have Hypomagnesaemia.

Could Buscopan cause Hypomagnesaemia?

Among these 23 people:

How long have people been on Buscopan when they have Hypomagnesaemia? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypomagnesaemia when taking Buscopan? *

  • female: 30.43 %
  • male: 69.57 %

What is the age of people who have Hypomagnesaemia when taking Buscopan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 8.7 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 26.09 %
  • 60+: 65.22 %

What are other drugs people take besides Buscopan? *

  1. Omeprazole: 7 people, 30.43%
  2. Paracetamol: 7 people, 30.43%
  3. Ramipril: 6 people, 26.09%
  4. Doxycycline: 6 people, 26.09%
  5. Quinine: 6 people, 26.09%
  6. Glucosamine: 6 people, 26.09%
  7. Co-Codamol: 6 people, 26.09%
  8. Finasteride: 6 people, 26.09%
  9. Pantoprazole: 6 people, 26.09%
  10. Magnesium Aspartate: 5 people, 21.74%

What are other side effects people have besides Hypomagnesaemia? *

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 12 people, 52.17%
  2. Constipation: 9 people, 39.13%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 34.78%
  4. Tetany (involuntary contraction of muscles): 8 people, 34.78%
  5. Hypokalemia (low potassium): 6 people, 26.09%
  6. Pneumonia: 6 people, 26.09%
  7. Abdominal Pain: 6 people, 26.09%
  8. Lower Respiratory Tract Infection: 5 people, 21.74%
  9. Diarrhea: 5 people, 21.74%
  10. Lung Adenocarcinoma (a form of non-small cell lung cancer): 4 people, 17.39%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 7 people, 30.43%
  2. Diarrhea: 4 people, 17.39%
  3. Oedema (fluid collection in tissue): 4 people, 17.39%
  4. Duodenal Ulcer Haemorrhage (bleeding duodenal ulcer): 4 people, 17.39%
  5. Abdominal Pain: 3 people, 13.04%
  6. Nausea And Vomiting: 3 people, 13.04%
  7. Nausea (feeling of having an urge to vomit): 3 people, 13.04%
  8. Abdominal Discomfort: 2 people, 8.70%
  9. Melaena (the passage of black, tarry stools): 2 people, 8.70%
  10. Gastritis (inflammation of stomach): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Buscopan and have Hypomagnesaemia?

- Check whether Hypomagnesaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buscopan:

Hypomagnesaemia treatments and more:

How severe was Hypomagnesaemia and when was it recovered:

Expand to all the drugs that have ingredients of hyoscine butylbromide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypomagnesaemia:

Browse all the conditions that are associated with Hypomagnesaemia:


How the study uses the data?

The study uses data from the FDA. It is based on hyoscine butylbromide (the active ingredients of Buscopan) and Buscopan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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