Buscopan and Skin blushing/flushing - a phase IV clinical study of FDA data
Summary:
Skin blushing/flushing is reported as a side effect among people who take Buscopan (hyoscine butylbromide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Crohn's disease.
The phase IV clinical study analyzes which people have Skin blushing/flushing when taking Buscopan. It is created by eHealthMe based on reports of 4,690 people who have side effects when taking Buscopan from the FDA, and is updated regularly.
What is Buscopan?
Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.
What is Skin blushing/flushing?
Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 2,010 drugs and 2,936 conditions by eHealthMe. Check the latest studies of Skin blushing/flushing.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
4,690 people reported to have side effects when taking Buscopan.
Among them, 47 people (1.0%) have Skin blushing/flushing.

Among these 47 people:
How long have people been on Buscopan when they have Skin blushing/flushing? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Skin blushing/flushing when taking Buscopan? *
- female: 79.07 %
- male: 20.93 %
What is the age of people who have Skin blushing/flushing when taking Buscopan? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 5.0 %
- 20-29: 0.0 %
- 30-39: 15.0 %
- 40-49: 17.5 %
- 50-59: 22.5 %
- 60+: 40.0 %
What are other drugs people take besides Buscopan? *
- Synthroid: 11 people, 23.40%
- Tylenol: 8 people, 17.02%
- Rituxan: 6 people, 12.77%
- Nexium: 6 people, 12.77%
- Rabeprazole: 6 people, 12.77%
- Benadryl: 5 people, 10.64%
- Zofran: 5 people, 10.64%
- Kombiglyze Xr: 4 people, 8.51%
- Invokana: 4 people, 8.51%
- Sulfatrim: 4 people, 8.51%
What are other side effects people have besides Skin blushing/flushing? *
- Chest Pain: 12 people, 25.53%
- Headache (pain in head): 12 people, 25.53%
- Itching: 12 people, 25.53%
- Infusion Related Reaction: 12 people, 25.53%
- Nausea (feeling of having an urge to vomit): 12 people, 25.53%
- Weight Decreased: 12 people, 25.53%
- Fever: 11 people, 23.40%
- Fatigue (feeling of tiredness): 11 people, 23.40%
- Joint Pain: 10 people, 21.28%
- Dyspnea (difficult or laboured breathing): 9 people, 19.15%
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 23.40%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 14.89%
- Gastric Disorder (disease of stomach): 5 people, 10.64%
- Pain: 5 people, 10.64%
- Thyroid Diseases: 4 people, 8.51%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 8.51%
- Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 4 people, 8.51%
- Neoplasm Malignant (cancer tumour): 4 people, 8.51%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 4.26%
- Colon Cancer: 2 people, 4.26%
* Approximation only. Some reports may have incomplete information.
Do you take Buscopan and have Skin blushing/flushing?
- Check whether Skin blushing/flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Buscopan:
- Buscopan (4,828 reports)
Skin blushing/flushing treatments and more:
- Skin blushing/flushing (117,676 reports)
How severe was Skin blushing/flushing and when was it recovered:
Expand to all the drugs that have ingredients of hyoscine butylbromide:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Buscopan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Skin blushing/flushing:
- Skin blushing/flushing (2,010 drugs)
Browse all the conditions that are associated with Skin blushing/flushing:
- Skin blushing/flushing (2,936 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on hyoscine butylbromide (the active ingredients of Buscopan) and Buscopan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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