Buspar and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Buspar (buspirone hydrochloride), especially for people who are female, 40-49 old, also take Aldactone, and have Hiv infection.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Buspar. It is created by eHealthMe based on reports of 17,598 people who have side effects when taking Buspar from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

On Aug, 09, 2026

17,598 people reported to have side effects when taking Buspar.
Among them, 22 people (0.13%) have Lactic acidosis.

Among these 22 people:

What is the gender of people who have Lactic acidosis when taking Buspar? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Lactic acidosis when taking Buspar? *

What are other drugs people take besides Buspar? *

What are other side effects people have besides Lactic acidosis? *

Cardiac Failure Congestive: 10 people, 45.45%
Hypotension (abnormally low blood pressure): 9 people, 40.91%
Weight Increased: 7 people, 31.82%
Chest Pain: 7 people, 31.82%
Fatigue (feeling of tiredness): 7 people, 31.82%
Blood Creatinine Increased: 6 people, 27.27%
Respiratory Distress (difficulty in breathing): 6 people, 27.27%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 6 people, 27.27%
Dyspnea (difficult or laboured breathing): 6 people, 27.27%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 27.27%

What are the existing conditions these people have? *

Hiv Infection: 5 people, 22.73%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 18.18%
Bipolar Disorder (mood disorder): 2 people, 9.09%
Type 2 Diabetes: 1 person, 4.55%
Rashes (redness): 1 person, 4.55%
Migraine (headache): 1 person, 4.55%
Birth Control: 1 person, 4.55%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.55%
Acne (skin problems that cause pimples): 1 person, 4.55%
Abdominal Distension: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buspar:

Buspar (20,463 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (995 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride (the active ingredients of Buspar) and Buspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.