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Buspar and Systemic lupus erythematosus - a phase IV clinical study of FDA data

Summary:

Systemic lupus erythematosus is reported as a side effect among people who take Buspar (buspirone hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Lasix, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Systemic lupus erythematosus when taking Buspar. It is created by eHealthMe based on reports of 17,598 people who have side effects when taking Buspar from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Systemic lupus erythematosus?

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 1,086 drugs and 1,645 conditions by eHealthMe. Check the latest studies of Systemic lupus erythematosus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

17,598 people reported to have side effects when taking Buspar.
Among them, 47 people (0.27%) have Systemic lupus erythematosus.

Could Buspar cause Systemic lupus erythematosus?

Among these 47 people:

How long have people been on Buspar when they have Systemic lupus erythematosus? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Systemic lupus erythematosus when taking Buspar? *

  • female: 95.74 %
  • male: 4.26 %

What is the age of people who have Systemic lupus erythematosus when taking Buspar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.86 %
  • 30-39: 14.29 %
  • 40-49: 57.14 %
  • 50-59: 17.14 %
  • 60+: 8.57 %

What are other drugs people take besides Buspar? *

  1. Lasix: 15 people, 31.91%
  2. Prilosec: 11 people, 23.40%
  3. Humira: 11 people, 23.40%
  4. Singulair: 11 people, 23.40%
  5. Lexapro: 10 people, 21.28%
  6. Ambien: 10 people, 21.28%
  7. Xyrem: 10 people, 21.28%
  8. Lyrica: 10 people, 21.28%
  9. Seroquel: 10 people, 21.28%
  10. Lamictal: 9 people, 19.15%

What are other side effects people have besides Systemic lupus erythematosus? *

  1. Fatigue (feeling of tiredness): 18 people, 38.30%
  2. Fall: 16 people, 34.04%
  3. Drug Ineffective: 16 people, 34.04%
  4. Fainting (loss of consciousness and postural tone): 16 people, 34.04%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 15 people, 31.91%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 14 people, 29.79%
  7. Nausea (feeling of having an urge to vomit): 14 people, 29.79%
  8. Rashes (redness): 13 people, 27.66%
  9. Pain: 13 people, 27.66%
  10. Dizziness: 12 people, 25.53%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 21.28%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 21.28%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 21.28%
  4. Pain: 9 people, 19.15%
  5. Diabetes: 8 people, 17.02%
  6. Dyspnea (difficult or laboured breathing): 6 people, 12.77%
  7. Nausea (feeling of having an urge to vomit): 6 people, 12.77%
  8. High Blood Pressure: 5 people, 10.64%
  9. Osteoporosis (bones weak and more likely to break): 5 people, 10.64%
  10. Candidiasis (candidiasis or thrush is a fungal infection): 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and have Systemic lupus erythematosus?

- Check whether Systemic lupus erythematosus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buspar:

Systemic lupus erythematosus treatments and more:

How severe was Systemic lupus erythematosus and when was it recovered:

Expand to all the drugs that have ingredients of buspirone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic lupus erythematosus:

Browse all the conditions that are associated with Systemic lupus erythematosus:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride (the active ingredients of Buspar) and Buspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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