Busulfan and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Busulfan (busulfan), especially for people who are female, 0-1 old, also take Cyclosporine, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Irritability when taking Busulfan. It is created by eHealthMe based on reports of 14,527 people who have side effects when taking Busulfan from the FDA, and is updated regularly.

What is Busulfan?

Busulfan has active ingredients of busulfan. eHealthMe is studying from 14,527 Busulfan users. Check the latest studies of Busulfan.

What is Irritability?

Irritability is found to be associated with 1,696 drugs and 2,461 conditions by eHealthMe. Check the latest studies of Irritability.



On Aug, 06, 2026

14,527 people reported to have side effects when taking Busulfan.
Among them, 13 people (0.09%) have Irritability.

Could Busulfan cause Irritability?

Among these 13 people:

What is the gender of people who have Irritability when taking Busulfan? *

  • female: 84.62 %
  • male: 15.38 %

What is the age of people who have Irritability when taking Busulfan? *

  • 0-1: 84.62 %
  • 2-9: 7.69 %
  • 10-19: 7.69 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Busulfan? *

  1. Cyclophosphamide: 4 people, 30.77%
  2. Cyclosporine: 4 people, 30.77%
  3. Mycophenolate Mofetil: 3 people, 23.08%
  4. Hydrocortisone: 2 people, 15.38%
  5. Methylprednisolone: 2 people, 15.38%
  6. Methotrexate: 2 people, 15.38%
  7. Dexamethasone: 2 people, 15.38%
  8. Etoposide: 2 people, 15.38%
  9. Fluconazole: 1 person, 7.69%
  10. Aldurazyme: 1 person, 7.69%

What are other side effects people have besides Irritability? *

  1. Fever: 9 people, 69.23%
  2. Nephropathy Toxic (damage to kidney due to toxins): 8 people, 61.54%
  3. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 8 people, 61.54%
  4. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 8 people, 61.54%
  5. Encephalitis Cytomegalovirus (inflammation of the brain due to cytomegalovirus): 7 people, 53.85%
  6. Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 7 people, 53.85%
  7. Drug Ineffective: 4 people, 30.77%
  8. Meningitis Viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 4 people, 30.77%
  9. Fatigue (feeling of tiredness): 3 people, 23.08%
  10. Encephalitis (inflammation of the brain): 3 people, 23.08%

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 9 people, 69.23%
  2. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 8 people, 61.54%
  3. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 8 people, 61.54%
  4. Encephalitis Cytomegalovirus (inflammation of the brain due to cytomegalovirus): 7 people, 53.85%
  5. Cytomegalovirus Infection: 7 people, 53.85%
  6. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 5 people, 38.46%
  7. Meningitis Viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 4 people, 30.77%
  8. Acute Graft Versus Host Disease In Skin (acute complication on skin following an allogeneic tissue/blood transplant): 3 people, 23.08%
  9. Acute Graft Versus Host Disease In Intestine (acute complication in intestine following an allogeneic tissue/blood transplant): 3 people, 23.08%
  10. Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Busulfan and have Irritability?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Busulfan:

Irritability treatments and more:

How severe was Irritability and when was it recovered:

Expand to all the drugs that have ingredients of busulfan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Busulfan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Browse all the conditions that are associated with Irritability:


How the study uses the data?

The study uses data from the FDA. It is based on busulfan (the active ingredients of Busulfan) and Busulfan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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