Caduet and Speech impairment (adult) - a phase IV clinical study of FDA data

Summary:

Speech impairment (adult) is reported as a side effect among people who take Caduet (amlodipine besylate; atorvastatin calcium), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Lexapro, and have Depression.

The phase IV clinical study analyzes which people have Speech impairment (adult) when taking Caduet. It is created by eHealthMe based on reports of 4,989 people who have side effects when taking Caduet from the FDA, and is updated regularly.

What is Caduet?

Caduet has active ingredients of amlodipine besylate; atorvastatin calcium. It is often used in high blood pressure. eHealthMe is studying from 5,157 Caduet users. Check the latest studies of Caduet.

What is Speech impairment (adult)?

Speech impairment (adult) (inability to speak (adult)) is found to be associated with 2,141 drugs and 3,591 conditions by eHealthMe. Check the latest studies of Speech impairment (adult).



On Apr, 10, 2026

4,989 people reported to have side effects when taking Caduet.
Among them, 18 people (0.36%) have Speech impairment (adult).

Could Caduet cause Speech impairment (adult)?

Among these 18 people:

How long have people been on Caduet when they have Speech impairment (adult)? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Speech impairment (adult) when taking Caduet? *

  • female: 47.06 %
  • male: 52.94 %

What is the age of people who have Speech impairment (adult) when taking Caduet? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.67 %
  • 40-49: 26.67 %
  • 50-59: 6.67 %
  • 60+: 60.0 %

What are other drugs people take besides Caduet? *

  1. Lasix: 4 people, 22.22%
  2. Lyrica: 4 people, 22.22%
  3. Lexapro: 4 people, 22.22%
  4. Plavix: 3 people, 16.67%
  5. Norvasc: 3 people, 16.67%
  6. Glucophage: 3 people, 16.67%
  7. Darvocet: 3 people, 16.67%
  8. Digoxin: 3 people, 16.67%
  9. Aspirin: 3 people, 16.67%
  10. Lisinopril: 3 people, 16.67%

What are other side effects people have besides Speech impairment (adult)? *

  1. Hypoaesthesia (reduced sense of touch or sensation): 5 people, 27.78%
  2. Nausea (feeling of having an urge to vomit): 5 people, 27.78%
  3. Pain: 5 people, 27.78%
  4. Abasia (inability to walk): 4 people, 22.22%
  5. Depression: 4 people, 22.22%
  6. Weakness: 4 people, 22.22%
  7. Acute Kidney Failure: 4 people, 22.22%
  8. Gait Disturbance: 4 people, 22.22%
  9. Drowsiness: 4 people, 22.22%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 16.67%

What are the existing conditions these people have? *

  1. Depression: 3 people, 16.67%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.11%
  3. Neuropathy Peripheral (surface nerve damage): 2 people, 11.11%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 11.11%
  5. Stress And Anxiety: 1 person, 5.56%
  6. Gastritis (inflammation of stomach): 1 person, 5.56%
  7. Asthma: 1 person, 5.56%
  8. Breast Cancer: 1 person, 5.56%
  9. Cardiac Hypertrophy (thickening of the heart muscle): 1 person, 5.56%
  10. Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Caduet and have Speech impairment (adult)?

- Check whether Speech impairment (adult) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Caduet:

Speech impairment (adult) treatments and more:

How severe was Speech impairment (adult) and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate; atorvastatin calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Caduet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Speech impairment (adult):

Browse all the conditions that are associated with Speech impairment (adult):


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; atorvastatin calcium (the active ingredients of Caduet) and Caduet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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