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Calcium ascorbate and Osteoarthritis - a phase IV clinical study of FDA data

Summary:

Osteoarthritis is reported as a side effect among people who take Calcium ascorbate (vitamin c (ascorbic acid)), especially for people who are female, 40-49 old, also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Osteoarthritis when taking Calcium ascorbate. It is created by eHealthMe based on reports of 1,009 people who have side effects when taking Calcium ascorbate from the FDA, and is updated regularly.

What is Calcium ascorbate?

Calcium ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,018 Calcium ascorbate users. Check the latest studies of Calcium ascorbate.

What is Osteoarthritis?

Osteoarthritis (a joint disease caused by cartilage loss in a joint) is found to be associated with 1,878 drugs and 2,647 conditions by eHealthMe. Check the latest studies of Osteoarthritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 31, 2026

1,009 people reported to have side effects when taking Calcium ascorbate.
Among them, 97 people (9.61%) have Osteoarthritis.

Could Calcium ascorbate cause Osteoarthritis?

Among these 97 people:

What is the gender of people who have Osteoarthritis when taking Calcium ascorbate? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Osteoarthritis when taking Calcium ascorbate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 92.19 %
  • 50-59: 0.0 %
  • 60+: 7.81 %

What are other drugs people take besides Calcium ascorbate? *

  1. Prednisone: 93 people, 95.88%
  2. Folic Acid: 90 people, 92.78%
  3. Actemra: 90 people, 92.78%
  4. Desoximetasone: 89 people, 91.75%
  5. Sulfasalazine: 89 people, 91.75%
  6. Cortisone Acetate: 88 people, 90.72%
  7. Simponi: 88 people, 90.72%
  8. Cimzia: 88 people, 90.72%
  9. Cosentyx: 87 people, 89.69%
  10. Fosamax: 86 people, 88.66%

What are other side effects people have besides Osteoarthritis? *

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 86 people, 88.66%
  2. Stomatitis (inflammation of mucous membrane of mouth): 85 people, 87.63%
  3. Urticaria (rash of round, red welts on the skin that itch intensely): 84 people, 86.60%
  4. High Blood Pressure: 82 people, 84.54%
  5. Confusional State: 82 people, 84.54%
  6. Dizziness: 81 people, 83.51%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 81 people, 83.51%
  8. Hypoaesthesia (reduced sense of touch or sensation): 80 people, 82.47%
  9. High Blood Cholesterol: 80 people, 82.47%
  10. Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 80 people, 82.47%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 92 people, 94.85%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 79 people, 81.44%
  3. Migraine (headache): 66 people, 68.04%
  4. Psoriasis (immune-mediated disease that affects the skin): 58 people, 59.79%
  5. Stress And Anxiety: 20 people, 20.62%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 12.37%
  7. Indigestion: 10 people, 10.31%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 9.28%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 7.22%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 6.19%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium ascorbate and have Osteoarthritis?

- Check whether Osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Calcium ascorbate:

Osteoarthritis treatments and more:

How severe was Osteoarthritis and when was it recovered:

Expand to all the drugs that have ingredients of vitamin c (ascorbic acid):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoarthritis:

Browse all the conditions that are associated with Osteoarthritis:

How the study uses the data?

The study uses data from the FDA. It is based on vitamin c (ascorbic acid) (the active ingredients of Calcium ascorbate) and Calcium ascorbate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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