Calcium and Hypertonia - a phase IV clinical study of FDA data

Summary:

Hypertonia is reported as a side effect among people who take Calcium (calcium), especially for people who are female, 60+ old, also take Aripiprazole, and have Major depression.

The phase IV clinical study analyzes which people have Hypertonia when taking Calcium. It is created by eHealthMe based on reports of 180,447 people who have side effects when taking Calcium from the FDA, and is updated regularly.

What is Calcium?

Calcium has active ingredients of calcium. It is often used in osteoporosis. eHealthMe is studying from 184,201 Calcium users. Check the latest studies of Calcium.

What is Hypertonia?

Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch) is found to be associated with 491 drugs and 692 conditions by eHealthMe. Check the latest studies of Hypertonia.



On Jul, 10, 2026

180,447 people reported to have side effects when taking Calcium.
Among them, 48 people (0.03%) have Hypertonia.

Could Calcium cause Hypertonia?

Among these 48 people:

What is the gender of people who have Hypertonia when taking Calcium? *

  • female: 80.43 %
  • male: 19.57 %

What is the age of people who have Hypertonia when taking Calcium? *

  • 0-1: 0.0 %
  • 2-9: 8.33 %
  • 10-19: 2.78 %
  • 20-29: 0.0 %
  • 30-39: 8.33 %
  • 40-49: 11.11 %
  • 50-59: 13.89 %
  • 60+: 55.56 %

What are other drugs people take besides Calcium? *

  1. Lorazepam: 6 people, 12.50%
  2. Ferrous Fumarate: 6 people, 12.50%
  3. Enbrel: 6 people, 12.50%
  4. Vitamin D: 6 people, 12.50%
  5. Olanzapine: 6 people, 12.50%
  6. Mirtazapine: 6 people, 12.50%
  7. Metformin: 6 people, 12.50%
  8. Hydrochlorothiazide: 6 people, 12.50%
  9. Aripiprazole: 6 people, 12.50%
  10. Vitamins: 5 people, 10.42%

What are other side effects people have besides Hypertonia? *

  1. Agitation (state of anxiety or nervous excitement): 10 people, 20.83%
  2. Weakness: 8 people, 16.67%
  3. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 8 people, 16.67%
  4. Hyperreflexia (overactive or over responsive reflexes): 7 people, 14.58%
  5. Gait Disturbance: 7 people, 14.58%
  6. Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 7 people, 14.58%
  7. Confusional State: 7 people, 14.58%
  8. Delirium (wild excitement): 6 people, 12.50%
  9. Insomnia (sleeplessness): 6 people, 12.50%
  10. Hyperhidrosis (abnormally increased sweating): 6 people, 12.50%

What are the existing conditions these people have? *

  1. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 6 people, 12.50%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 10.42%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 10.42%
  4. Migraine (headache): 3 people, 6.25%
  5. Haemolytic Anaemia (anaemia due to haemolysis): 3 people, 6.25%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 6.25%
  7. Calcium Deficiency (lack of calcium): 2 people, 4.17%
  8. Gait Disturbance: 2 people, 4.17%
  9. Nausea (feeling of having an urge to vomit): 2 people, 4.17%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium and have Hypertonia?

- Check whether Hypertonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Calcium:

Hypertonia treatments and more:

How severe was Hypertonia and when was it recovered:

Expand to all the drugs that have ingredients of calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonia:

Browse all the conditions that are associated with Hypertonia:


How the study uses the data?

The study uses data from the FDA. It is based on calcium (the active ingredients of Calcium) and Calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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