Canasa and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Canasa (mesalamine), especially for people who are male, 60+ old, also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Canasa. It is created by eHealthMe based on reports of 1,606 people who have side effects when taking Canasa from the FDA, and is updated regularly.

What is Canasa?

Canasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 1,676 Canasa users. Check the latest studies of Canasa.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,499 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

1,606 people reported to have side effects when taking Canasa.
Among them, 30 people (1.87%) have Acute kidney failure.

Could Canasa cause Acute kidney failure?

Among these 30 people:

What is the gender of people who have Acute kidney failure when taking Canasa? *

female: 22.22 %
male: 77.78 %

What is the age of people who have Acute kidney failure when taking Canasa? *

What are other drugs people take besides Canasa? *

What are other side effects people have besides Acute kidney failure? *

Cardiac Arrest: 13 people, 43.33%
Weight Decreased: 12 people, 40.00%
High Blood Pressure: 12 people, 40.00%
Peritonitis Bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 11 people, 36.67%
Prostatic Specific Antigen Increased: 11 people, 36.67%
Cirrhosis Alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism): 9 people, 30.00%
Cardiac Failure: 9 people, 30.00%
Oedema Peripheral (superficial swelling): 9 people, 30.00%
Multiple Injuries: 8 people, 26.67%
Hyperkalemia (damage to or disease of the kidney): 8 people, 26.67%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 36.67%
High Blood Pressure: 7 people, 23.33%
Pain: 6 people, 20.00%
High Blood Cholesterol: 5 people, 16.67%
Depression: 4 people, 13.33%
Stress And Anxiety: 4 people, 13.33%
Nausea (feeling of having an urge to vomit): 3 people, 10.00%
Diabetes: 3 people, 10.00%
Erection Problems: 2 people, 6.67%
Enlarged Prostate: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Canasa and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Canasa:

Canasa (1,676 reports)

Browse all side effects of Canasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,836 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,499 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Canasa) and Canasa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.