Captopril and Adverse event - a phase IV clinical study of FDA data


Adverse event is found among people who take Captopril, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Captopril and have Adverse event. It is created by eHealthMe based on reports of 16,585 people who have side effects when taking Captopril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 26, 2022

16,585 people reported to have side effects when taking Captopril.
Among them, 21 people (0.13%) have Adverse event.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 16,731 Captopril users for its effectiveness, alternative drugs and more.

What is Adverse event?

Adverse event is found to be associated with 2,126 drugs and 1,486 conditions by eHealthMe.

Number of Captopril and Adverse event reports submitted per year:

Could Captopril cause Adverse event?

Time on Captopril when people have Adverse event *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Adverse event when taking Captopril *:

  • female: 42.11 %
  • male: 57.89 %

Age of people who have Adverse event when taking Captopril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 33.33 %
  • 60+: 60.0 %

Common drugs people take besides Captopril *:

  1. Aspirin: 9 people, 42.86%
  2. Plavix: 4 people, 19.05%
  3. Xanax: 4 people, 19.05%
  4. Protonix: 3 people, 14.29%
  5. Naproxen Sodium: 3 people, 14.29%
  6. Effexor: 3 people, 14.29%
  7. Fosamax: 3 people, 14.29%
  8. Januvia: 2 people, 9.52%
  9. Norvasc: 2 people, 9.52%
  10. Metformin Hydrochloride: 2 people, 9.52%

Common side effects people have besides Adverse event *:

  1. Abdominal Discomfort: 4 people, 19.05%
  2. Weakness: 4 people, 19.05%
  3. Nephritis (inflammation of the nephrons in the kidneys): 3 people, 14.29%
  4. Cholecystitis Acute (rapid infection of gallbladder): 3 people, 14.29%
  5. Thrombotic Thrombocytopenic Purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 3 people, 14.29%
  6. Cough: 3 people, 14.29%
  7. Pneumonia: 3 people, 14.29%
  8. Infection: 3 people, 14.29%
  9. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 14.29%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 9.52%

Common conditions people have *:

  1. Stress And Anxiety: 3 people, 14.29%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 14.29%
  3. Depression: 3 people, 14.29%
  4. Abdominal Pain Upper: 3 people, 14.29%
  5. Hepatitis C: 2 people, 9.52%
  6. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.52%
  7. Renal Impairment (severely reduced kidney function): 2 people, 9.52%
  8. Diabetes: 2 people, 9.52%
  9. Erection Problems: 1 person, 4.76%
  10. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Captopril and have Adverse event?

Check whether Adverse event is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Adverse event and when was it recovered:

Expand to all the drugs that have ingredients of captopril:

Alternative drugs to, pros and cons of Captopril:

Common Captopril side effects:

Browse all side effects of Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Adverse event treatments and more:

COVID vaccines that are related to Adverse event:

Common drugs associated with Adverse event:

All the drugs that are associated with Adverse event:

Common conditions associated with Adverse event:

All the conditions that are associated with Adverse event:

How the study uses the data?

The study uses data from the FDA. It is based on captopril (the active ingredients of Captopril) and Captopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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