Captopril and Adverse event - a phase IV clinical study of FDA data
Summary:
Adverse event is found among people who take Captopril, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Captopril and have Adverse event. It is created by eHealthMe based on reports of 16,585 people who have side effects when taking Captopril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
16,585 people reported to have side effects when taking Captopril.
Among them, 21 people (0.13%) have Adverse event.
What is Captopril?
Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 16,731 Captopril users for its effectiveness, alternative drugs and more.
What is Adverse event?
Adverse event is found to be associated with 2,126 drugs and 1,486 conditions by eHealthMe.
Number of Captopril and Adverse event reports submitted per year:

Time on Captopril when people have Adverse event *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 100 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Adverse event when taking Captopril *:
- female: 42.11 %
- male: 57.89 %
Age of people who have Adverse event when taking Captopril *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 6.67 %
- 50-59: 33.33 %
- 60+: 60.0 %
Common drugs people take besides Captopril *:
- Aspirin: 9 people, 42.86%
- Plavix: 4 people, 19.05%
- Xanax: 4 people, 19.05%
- Protonix: 3 people, 14.29%
- Naproxen Sodium: 3 people, 14.29%
- Effexor: 3 people, 14.29%
- Fosamax: 3 people, 14.29%
- Januvia: 2 people, 9.52%
- Norvasc: 2 people, 9.52%
- Metformin Hydrochloride: 2 people, 9.52%
Common side effects people have besides Adverse event *:
- Abdominal Discomfort: 4 people, 19.05%
- Weakness: 4 people, 19.05%
- Nephritis (inflammation of the nephrons in the kidneys): 3 people, 14.29%
- Cholecystitis Acute (rapid infection of gallbladder): 3 people, 14.29%
- Thrombotic Thrombocytopenic Purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 3 people, 14.29%
- Cough: 3 people, 14.29%
- Pneumonia: 3 people, 14.29%
- Infection: 3 people, 14.29%
- Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 14.29%
- Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 9.52%
Common conditions people have *:
- Stress And Anxiety: 3 people, 14.29%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 14.29%
- Depression: 3 people, 14.29%
- Abdominal Pain Upper: 3 people, 14.29%
- Hepatitis C: 2 people, 9.52%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.52%
- Renal Impairment (severely reduced kidney function): 2 people, 9.52%
- Diabetes: 2 people, 9.52%
- Erection Problems: 1 person, 4.76%
- Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 1 person, 4.76%
* Approximation only. Some reports may have incomplete information.
Do you take Captopril and have Adverse event?
Check whether Adverse event is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Adverse event and when was it recovered:
Expand to all the drugs that have ingredients of captopril:
Alternative drugs to, pros and cons of Captopril:
- Captopril (16,731 reports)
Common Captopril side effects:
- High blood pressure: 1,290 reports
- Weakness: 936 reports
- Breathing difficulty: 880 reports
- Drug ineffective: 839 reports
- Hypotension (abnormally low blood pressure): 831 reports
- Pain: 810 reports
- Fatigue (feeling of tiredness): 772 reports
- Pneumonia: 755 reports
Browse all side effects of Captopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zAdverse event treatments and more:
- Adverse event (88,067 reports)
COVID vaccines that are related to Adverse event:
- Adverse event in Moderna COVID Vaccine
- Adverse event in Pfizer BioNTech Covid Vaccine
- Adverse event in Johnson and Johnson Covid Vaccine
Common drugs associated with Adverse event:
- Enbrel: 4,081 reports
- Orencia: 3,669 reports
- Fosamax: 3,648 reports
- Vioxx: 3,000 reports
- Methotrexate: 2,943 reports
- Eliquis: 2,855 reports
- Prednisone: 2,810 reports
- Remicade: 2,650 reports
- Humira: 2,503 reports
- Xarelto: 2,282 reports
All the drugs that are associated with Adverse event:
- Adverse event (2,126 drugs)
Common conditions associated with Adverse event:
- Rheumatoid arthritis: 5,174 reports
- Osteoporosis: 2,799 reports
- Multiple sclerosis: 2,408 reports
- Multiple myeloma: 1,465 reports
- Pain: 1,411 reports
- High blood cholesterol: 1,398 reports
- High blood pressure: 1,361 reports
- Depression: 1,258 reports
All the conditions that are associated with Adverse event:
- Adverse event (1,486 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on captopril (the active ingredients of Captopril) and Captopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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