Carboplatin and Toxic encephalopathy - a phase IV clinical study of FDA data

Summary:

Toxic encephalopathy is reported as a side effect among people who take Carboplatin (carboplatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Etoposide, and have Neuroblastoma.

The phase IV clinical study analyzes which people have Toxic encephalopathy when taking Carboplatin. It is created by eHealthMe based on reports of 127,949 people who have side effects when taking Carboplatin from the FDA, and is updated regularly.

What is Carboplatin?

Carboplatin has active ingredients of carboplatin. It is often used in cancer. eHealthMe is studying from 128,210 Carboplatin users. Check the latest studies of Carboplatin.

What is Toxic encephalopathy?

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) is found to be associated with 424 drugs and 615 conditions by eHealthMe. Check the latest studies of Toxic encephalopathy.

On Jul, 08, 2026

127,949 people reported to have side effects when taking Carboplatin.
Among them, 49 people (0.04%) have Toxic encephalopathy.

Could Carboplatin cause Toxic encephalopathy?

Among these 49 people:

How long have people been on Carboplatin when they have Toxic encephalopathy? *

What is the gender of people who have Toxic encephalopathy when taking Carboplatin? *

female: 63.83 %
male: 36.17 %

What is the age of people who have Toxic encephalopathy when taking Carboplatin? *

What are other drugs people take besides Carboplatin? *

What are other side effects people have besides Toxic encephalopathy? *

Cardiac Failure: 4 people, 8.16%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 8.16%
Myelosuppression (a decrease in the production of blood cells): 3 people, 6.12%
Infection: 3 people, 6.12%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 3 people, 6.12%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 6.12%
Pneumonia: 2 people, 4.08%
Aspartate Aminotransferase Increased: 2 people, 4.08%
Mucosal Inflammation (infection of mucous membrane): 2 people, 4.08%
Nausea (feeling of having an urge to vomit): 2 people, 4.08%

What are the existing conditions these people have? *

Neuroblastoma (a cancer that forms in your nerve tissue): 8 people, 16.33%
Burkitt's Lymphoma (cancer of the lymphatic system): 4 people, 8.16%
Clear Cell Sarcoma Of The Kidney (uncontrollably growing cancer of kidney from non cancerous cell): 4 people, 8.16%
High Blood Pressure: 4 people, 8.16%
Metastases To Peritoneum (cancer spreads to peritoneum): 4 people, 8.16%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 6.12%
Rhabdoid Tumor Of The Kidney: 3 people, 6.12%
Neuroblastoma Recurrent (reoccurrence of a cancer that forms in your nerve tissue): 3 people, 6.12%
Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 6.12%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Carboplatin and have Toxic encephalopathy?

- Check whether Toxic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Carboplatin:

Carboplatin (128,210 reports)

Browse all side effects of Carboplatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toxic encephalopathy:

Toxic encephalopathy (424 drugs)

Browse all the conditions that are associated with Toxic encephalopathy:

Toxic encephalopathy (615 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Zakaria S, Lu KY, Nussenblatt V, Browner I, "Atrial flutter associated with carboplatin administration", Annals of Pharmacotherapy, 2011 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on carboplatin (the active ingredients of Carboplatin) and Carboplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.