Cardizem and Bone marrow depression - a phase IV clinical study of FDA data

Summary:

Bone marrow depression is reported as a side effect among people who take Cardizem (diltiazem hydrochloride), especially for people who are male, 60+ old, also take Vitamin E, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Bone marrow depression when taking Cardizem. It is created by eHealthMe based on reports of 27,075 people who have side effects when taking Cardizem from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Bone marrow depression?

Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells) is found to be associated with 351 drugs and 465 conditions by eHealthMe. Check the latest studies of Bone marrow depression.

On Aug, 09, 2026

27,075 people reported to have side effects when taking Cardizem.
Among them, 23 people (0.08%) have Bone marrow depression.

Could Cardizem cause Bone marrow depression?

Among these 23 people:

What is the gender of people who have Bone marrow depression when taking Cardizem? *

female: 17.39 %
male: 82.61 %

What is the age of people who have Bone marrow depression when taking Cardizem? *

What are other drugs people take besides Cardizem? *

What are other side effects people have besides Bone marrow depression? *

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 13 people, 56.52%
Weight Decreased: 8 people, 34.78%
Chest Pain: 8 people, 34.78%
Aplastic Anemia: 6 people, 26.09%
Fatigue (feeling of tiredness): 5 people, 21.74%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 21.74%
Haemoglobin Decreased: 4 people, 17.39%
Eosinophil Count Increased: 4 people, 17.39%
Weakness: 4 people, 17.39%
Oedema Peripheral (superficial swelling): 3 people, 13.04%

What are the existing conditions these people have? *

Type 2 Diabetes: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and have Bone marrow depression?

- Check whether Bone marrow depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardizem:

Cardizem (28,014 reports)

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow depression:

Bone marrow depression (351 drugs)

Browse all the conditions that are associated with Bone marrow depression:

Bone marrow depression (465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Cardizem) and Cardizem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.