Cardizem and Interstitial lung disease - a phase IV clinical study of FDA data

Summary:

Interstitial lung disease is reported as a side effect among people who take Cardizem (diltiazem hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Interstitial lung disease when taking Cardizem. It is created by eHealthMe based on reports of 27,075 people who have side effects when taking Cardizem from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Interstitial lung disease?

Interstitial lung disease is found to be associated with 1,500 drugs and 1,839 conditions by eHealthMe. Check the latest studies of Interstitial lung disease.

On Jul, 06, 2026

27,075 people reported to have side effects when taking Cardizem.
Among them, 44 people (0.16%) have Interstitial lung disease.

Could Cardizem cause Interstitial lung disease?

Among these 44 people:

How long have people been on Cardizem when they have Interstitial lung disease? *

What is the gender of people who have Interstitial lung disease when taking Cardizem? *

female: 65.85 %
male: 34.15 %

What is the age of people who have Interstitial lung disease when taking Cardizem? *

What are other drugs people take besides Cardizem? *

What are other side effects people have besides Interstitial lung disease? *

Dyspnea (difficult or laboured breathing): 20 people, 45.45%
Pneumonia: 17 people, 38.64%
Chest Pain: 15 people, 34.09%
Nausea (feeling of having an urge to vomit): 13 people, 29.55%
Cardiac Failure Congestive: 12 people, 27.27%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 12 people, 27.27%
Headache (pain in head): 11 people, 25.00%
Anaemia (lack of blood): 10 people, 22.73%
Back Pain: 10 people, 22.73%
Hypotension (abnormally low blood pressure): 9 people, 20.45%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 6.82%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 6.82%
Quit Smoking: 2 people, 4.55%
Multiple Myeloma (cancer of the plasma cells): 2 people, 4.55%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 2.27%
High Blood Cholesterol: 1 person, 2.27%
Back Pain: 1 person, 2.27%
Breast Cancer Metastatic: 1 person, 2.27%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 2.27%
Candidiasis (candidiasis or thrush is a fungal infection): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and have Interstitial lung disease?

- Check whether Interstitial lung disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardizem:

Cardizem (28,014 reports)

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial lung disease:

Interstitial lung disease (1,500 drugs)

Browse all the conditions that are associated with Interstitial lung disease:

Interstitial lung disease (1,839 conditions)

Related publications that referenced our studies

Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Kato, M., Oiso, N., Nozaki, Y., Inoue, A., Hosono, Y., Funauchi, M., ... & Kawada, A., "Antitumor necrosis factor alpha inhibitor‐induced dermatomyositis and interstitial lung disease with anti‐PL 12 autoantibody: Signs of antisynthetase syndrome", The Journal of dermatology, 2012 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Kato, M., Oiso, N., Nozaki, Y., Inoue, A., Hosono, Y., Funauchi, M., ... & Kawada, A., "Antitumor necrosis factor alpha inhibitor‐induced dermatomyositis and interstitial lung disease with anti‐PL 12 autoantibody: Signs of antisynthetase syndrome", The Journal of dermatology, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Cardizem) and Cardizem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.