Topamax and Ceftin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Ceftin (cefuroxime axetil). Common drug interactions include ear pain among females and cerebellar ataxia among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Ceftin. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Ceftin?

Ceftin has active ingredients of cefuroxime axetil. It is often used in sinusitis. eHealthMe is studying from 4,333 Ceftin users. Check the latest studies of Ceftin.

On Jul, 06, 2026

67 people who take Topamax and Ceftin together, and have interactions are studied.

What are the common drug interactions of Topamax and Ceftin, by gender? *:

female:

Ear pain
Emotional distress
Essential tremor
Feeling drunk
Gastrointestinal tract irritation
Head discomfort
Head injury
Hepatotoxicity (chemical-driven liver damage)
Hip fracture
Hyperacusis (disorder in loudness perception)

male:

Cerebellar ataxia (loss of coordination)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Speech disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Asthenia (weakness)
Chest discomfort
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deafness neurosensory
Dental plaque (film of mucus and bacteria deposited on the teeth that encourages the development of dental caries)

What are the common drug interactions of Topamax and Ceftin, by age (0-1 to 60+)? *:

0-1:

Cerebral haemorrhage neonatal (bleeding in brain of baby of less than 1 month age)
Mitral valve incompetence (inefficient heart valve)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Right atrial dilatation (enlargement of the right atrium chamber of heart)
Right ventricular hypertrophy (right ventricular enlargement)
Tricuspid valve incompetence (inefficient heart valve)

2-9:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Cardiac disorder
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depressed level of consciousness
Hepatotoxicity (chemical-driven liver damage)
Hyperammonaemia
Increased bronchial secretion
Laryngeal oedema (swelling of larynx)

10-19:

n/a

20-29:

Abdominal discomfort
Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholesterosis (abnormal deposition of cholesterol in tissues)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Faeces discoloured
Hypokalaemia (low potassium)

30-39:

Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Drug ineffective
Head injury
Insomnia (sleeplessness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Poor quality sleep

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Cerebellar ataxia (loss of coordination)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Gait disturbance
Headache (pain in head)
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Pulmonary embolism (blockage of the main artery of the lung)
Speech disorder

50-59:

Drug hypersensitivity
Drug intolerance (drug sensitivity)
Drug ineffective
Anxiety
Aortic valve incompetence
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Cardiac failure congestive
Diarrhoea
Dry mouth
Dysgeusia (disorder of the sense of taste)

60+:

Headache (pain in head)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Respiratory tract congestion (blockage on respiratory system)
Viral infection
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Constipation

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 14.93%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.43%
Immunodeficiency Common Variable: 9 people, 13.43%
Depression: 9 people, 13.43%
Stress And Anxiety: 8 people, 11.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 10.45%
Asthma: 7 people, 10.45%
Weakness: 4 people, 5.97%
Type 1 Diabetes: 4 people, 5.97%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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