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Cardizem and Prothrombin level decreased - a phase IV clinical study of FDA data

Summary:

Prothrombin level decreased is reported as a side effect among people who take Cardizem (diltiazem hydrochloride), especially for people who are female, 60+ old, also take Coumadin, and have Deep venous thrombosis.

The phase IV clinical study analyzes which people have Prothrombin level decreased when taking Cardizem. It is created by eHealthMe based on reports of 27,075 people who have side effects when taking Cardizem from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Prothrombin level decreased?

Prothrombin level decreased is found to be associated with 205 drugs and 465 conditions by eHealthMe. Check the latest studies of Prothrombin level decreased.

On Jul, 09, 2026

27,075 people reported to have side effects when taking Cardizem.
Among them, 13 people (0.05%) have Prothrombin level decreased.

Could Cardizem cause Prothrombin level decreased?

Among these 13 people:

What is the gender of people who have Prothrombin level decreased when taking Cardizem? *

  • female: 69.23 %
  • male: 30.77 %

What is the age of people who have Prothrombin level decreased when taking Cardizem? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 18.18 %
  • 50-59: 36.36 %
  • 60+: 45.45 %

What are other drugs people take besides Cardizem? *

  1. Coumadin: 7 people, 53.85%
  2. Lasix: 4 people, 30.77%
  3. Zantac: 3 people, 23.08%
  4. Digoxin: 3 people, 23.08%
  5. Warfarin Sodium: 2 people, 15.38%
  6. Ventolin: 2 people, 15.38%
  7. Glucophage: 2 people, 15.38%
  8. Zestril: 2 people, 15.38%
  9. Diflucan: 2 people, 15.38%
  10. Zaroxolyn: 2 people, 15.38%

What are other side effects people have besides Prothrombin level decreased? *

  1. Weight Increased: 2 people, 15.38%
  2. Weakness: 2 people, 15.38%
  3. Weight Decreased: 2 people, 15.38%
  4. Hepatocellular Damage (liver damage): 2 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  6. Prothrombin Level Increased: 2 people, 15.38%
  7. Fatigue (feeling of tiredness): 2 people, 15.38%
  8. Ejection Fraction Abnormal (abnormality in percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 1 person, 7.69%
  9. Hepatomegaly (abnormal enlargement of the liver): 1 person, 7.69%
  10. Hepatic Failure (liver failure): 1 person, 7.69%

What are the existing conditions these people have? *

  1. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 7.69%
  2. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and have Prothrombin level decreased?

- Check whether Prothrombin level decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardizem:

Prothrombin level decreased treatments and more:

How severe was Prothrombin level decreased and when was it recovered:

Expand to all the drugs that have ingredients of diltiazem hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prothrombin level decreased:

Browse all the conditions that are associated with Prothrombin level decreased:

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Cardizem) and Cardizem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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