Cardizem and Uterine leiomyoma - a phase IV clinical study of FDA data

Summary:

Uterine leiomyoma is reported as a side effect among people who take Cardizem (diltiazem hydrochloride), especially for people who are 50-59 old, have been taking the drug for 10+ years also take Xanax, and have Menopausal symptoms.

The phase IV clinical study analyzes which people have Uterine leiomyoma when taking Cardizem. It is created by eHealthMe based on reports of 27,075 people who have side effects when taking Cardizem from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Uterine leiomyoma?

Uterine leiomyoma (uterine benign tumour derived from smooth muscle) is found to be associated with 786 drugs and 709 conditions by eHealthMe. Check the latest studies of Uterine leiomyoma.

On Jul, 21, 2026

27,075 people reported to have side effects when taking Cardizem.
Among them, 17 people (0.06%) have Uterine leiomyoma.

Among these 17 people:

How long have people been on Cardizem when they have Uterine leiomyoma? *

What is the age of people who have Uterine leiomyoma when taking Cardizem? *

What are other drugs people take besides Cardizem? *

What are other side effects people have besides Uterine leiomyoma? *

Chest Pain: 10 people, 58.82%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 10 people, 58.82%
Fatigue (feeling of tiredness): 8 people, 47.06%
Back Pain: 8 people, 47.06%
Pain In Extremity: 7 people, 41.18%
Enlarged Heart: 7 people, 41.18%
Indigestion: 7 people, 41.18%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 5 people, 29.41%
Weight Increased: 5 people, 29.41%
Insomnia (sleeplessness): 5 people, 29.41%

What are the existing conditions these people have? *

Menopausal Symptoms: 4 people, 23.53%
High Blood Cholesterol: 3 people, 17.65%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.88%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and have Uterine leiomyoma?

- Check whether Uterine leiomyoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardizem:

Cardizem (28,014 reports)

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uterine leiomyoma:

Uterine leiomyoma (786 drugs)

Browse all the conditions that are associated with Uterine leiomyoma:

Uterine leiomyoma (709 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Cardizem) and Cardizem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.