Carpine and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Carpine (pilocarpine hydrochloride), especially for people who are female, 60+ old, also take Humira, and have Back pain.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Carpine. It is created by eHealthMe based on reports of 5,521 people who have side effects when taking Carpine from the FDA, and is updated regularly.

What is Carpine?

Carpine has active ingredients of pilocarpine hydrochloride. eHealthMe is studying from 5,561 Carpine users. Check the latest studies of Carpine.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 860 drugs and 1,062 conditions by eHealthMe. Check the latest studies of Hip joint replacement.

On Jun, 02, 2026

5,521 people reported to have side effects when taking Carpine.
Among them, 33 people (0.6%) have Hip joint replacement.

Could Carpine cause Hip joint replacement?

Among these 33 people:

What is the gender of people who have Hip joint replacement when taking Carpine? *

female: 62.96 %
male: 37.04 %

What is the age of people who have Hip joint replacement when taking Carpine? *

What are other drugs people take besides Carpine? *

What are other side effects people have besides Hip joint replacement? *

Drug Ineffective: 18 people, 54.55%
Pain: 18 people, 54.55%
Muscle Aches (muscle pain): 15 people, 45.45%
Weakness: 15 people, 45.45%
Uveitis (inflammation of the uvea): 14 people, 42.42%
Osteoporosis (bones weak and more likely to break): 14 people, 42.42%
Impaired Work Ability: 14 people, 42.42%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 14 people, 42.42%
Headache (pain in head): 14 people, 42.42%
Abasia (inability to walk): 12 people, 36.36%

What are the existing conditions these people have? *

Back Pain: 8 people, 24.24%
Diabetes: 7 people, 21.21%
Cardiac Disorder: 6 people, 18.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 15.15%
Intraocular Pressure Increased: 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Abnormal Sensation In Eye: 4 people, 12.12%
Pain: 2 people, 6.06%
Urinary Tract Infection: 1 person, 3.03%
Oral Candidiasis (fungal infection of mouth): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Carpine and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Carpine:

Carpine (5,561 reports)

Browse all side effects of Carpine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Hip joint replacement (860 drugs)

Browse all the conditions that are associated with Hip joint replacement:

Hip joint replacement (1,062 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pilocarpine hydrochloride (the active ingredients of Carpine) and Carpine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.