Carvedilol and Thrombotic microangiopathy - a phase IV clinical study of FDA data

Summary:

Thrombotic microangiopathy is reported as a side effect among people who take Carvedilol (carvedilol), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Amlodipine, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Thrombotic microangiopathy when taking Carvedilol. It is created by eHealthMe based on reports of 110,224 people who have side effects when taking Carvedilol from the FDA, and is updated regularly.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,651 Carvedilol users. Check the latest studies of Carvedilol.

What is Thrombotic microangiopathy?

Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury) is found to be associated with 468 drugs and 672 conditions by eHealthMe. Check the latest studies of Thrombotic microangiopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

110,224 people reported to have side effects when taking Carvedilol.
Among them, 42 people (0.04%) have Thrombotic microangiopathy.

Could Carvedilol cause Thrombotic microangiopathy?

Among these 42 people:

How long have people been on Carvedilol when they have Thrombotic microangiopathy? *

What is the gender of people who have Thrombotic microangiopathy when taking Carvedilol? *

female: 25 %
male: 75 %

What is the age of people who have Thrombotic microangiopathy when taking Carvedilol? *

What are other drugs people take besides Carvedilol? *

What are other side effects people have besides Thrombotic microangiopathy? *

Cytomegalovirus Infection: 7 people, 16.67%
Pyelonephritis Acute (sudden inflammation of kidney caused by bacteria): 7 people, 16.67%
Renal Impairment (severely reduced kidney function): 6 people, 14.29%
Bone Marrow Toxicity (decrease in cells responsible for providing immunity, carrying oxygen, and those responsible for normal blood clotting): 6 people, 14.29%
Thrombocytopenia (decrease of platelets in blood): 5 people, 11.90%
Acute Kidney Failure: 3 people, 7.14%
Blood Creatinine Increased: 3 people, 7.14%
Interstitial Nephritis (inflammation of the kidney): 3 people, 7.14%
Renal Tubular Necrosis (death of kidney tubules): 3 people, 7.14%
Oedema Peripheral (superficial swelling): 3 people, 7.14%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 5 people, 11.90%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 7.14%
Hypotension (abnormally low blood pressure): 3 people, 7.14%
Pain: 3 people, 7.14%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 4.76%
Cytomegalovirus Infection: 2 people, 4.76%
Type 2 Diabetes: 2 people, 4.76%
Depression: 2 people, 4.76%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 4.76%
Diabetes: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Carvedilol and have Thrombotic microangiopathy?

- Check whether Thrombotic microangiopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Carvedilol:

Carvedilol (112,651 reports)

Browse all side effects of Carvedilol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombotic microangiopathy:

Thrombotic microangiopathy (468 drugs)

Browse all the conditions that are associated with Thrombotic microangiopathy:

Thrombotic microangiopathy (672 conditions)

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Carvedilol) and Carvedilol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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