Cascara and Fatigue - a phase IV clinical study of FDA data
Summary:
Fatigue is reported as a side effect among people who take Cascara (cascara), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Metformin, and have Weight decreased.
The phase IV clinical study analyzes which people have Fatigue when taking Cascara. It is created by eHealthMe based on reports of 296 people who have side effects when taking Cascara from the FDA, and is updated regularly.
What is Cascara?
Cascara has active ingredients of cascara. eHealthMe is studying from 302 Cascara users. Check the latest studies of Cascara.
What is Fatigue?
Fatigue (feeling of tiredness) is found to be associated with 4,026 drugs and 6,380 conditions by eHealthMe. Check the latest studies of Fatigue.
296 people reported to have side effects when taking Cascara.
Among them, 47 people (15.88%) have Fatigue.

Among these 47 people:
How long have people been on Cascara when they have Fatigue? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 90.91 %
- 1 - 2 years: 9.09 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Fatigue when taking Cascara? *
- female: 97.56 %
- male: 2.44 %
What is the age of people who have Fatigue when taking Cascara? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 2.78 %
- 30-39: 0.0 %
- 40-49: 72.22 %
- 50-59: 8.33 %
- 60+: 16.67 %
What are other drugs people take besides Cascara? *
- Metformin: 22 people, 46.81%
- Centella Asiatica: 21 people, 44.68%
- Chromium Picolinate: 20 people, 42.55%
- Magnesium: 9 people, 19.15%
- Senna: 8 people, 17.02%
- Vitamin C: 8 people, 17.02%
- Amlodipine: 7 people, 14.89%
- Jakafi: 7 people, 14.89%
- Potassium: 7 people, 14.89%
- Fish Oil: 7 people, 14.89%
What are other side effects people have besides Fatigue? *
- Headache (pain in head): 32 people, 68.09%
- Thalamic Infarction (tissue death of thalamus part of brain): 25 people, 53.19%
- Cerebral Venous Thrombosis (clot in brains venous blood system): 25 people, 53.19%
- Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain): 21 people, 44.68%
- Motormental Retardation (a slowing-down of thought and a reduction of physical work): 17 people, 36.17%
- Slow Response To Stimuli (slow response by nerves): 12 people, 25.53%
- Drowsiness: 7 people, 14.89%
- Muscle Aches (muscle pain): 7 people, 14.89%
- Dyspnea (difficult or laboured breathing): 7 people, 14.89%
- Bone Pain: 7 people, 14.89%
What are the existing conditions these people have? *
- Birth Control: 24 people, 51.06%
- Weight Decreased: 24 people, 51.06%
- Ventricular Extrasystoles (premature cardiac contraction): 23 people, 48.94%
- Primary Myelofibrosis (primary disorder of the bone marrow): 7 people, 14.89%
- Weight Loss: 6 people, 12.77%
- Neck Pain: 5 people, 10.64%
- Headache (pain in head): 5 people, 10.64%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.51%
- Pain: 2 people, 4.26%
- Gastrointestinal Carcinoma (cancer of stomach or intestine): 2 people, 4.26%
* Approximation only. Some reports may have incomplete information.
Do you take Cascara and have Fatigue?
- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Cascara:
- Cascara (302 reports)
Fatigue treatments and more:
- Fatigue (967,537 reports)
How severe was Fatigue and when was it recovered:
Expand to all the drugs that have ingredients of cascara:
- Fatigue and drugs with ingredients of cascara (57 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cascara:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Fatigue:
- Fatigue (4,026 drugs)
Browse all the conditions that are associated with Fatigue:
- Fatigue (6,380 conditions)
Related publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on cascara (the active ingredients of Cascara) and Cascara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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