Levaquin and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is reported as a side effect among people who take Levaquin (levofloxacin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ambien, and have Myelodysplastic syndrome.

The phase IV clinical study analyzes which people have Brain herniation when taking Levaquin. It is created by eHealthMe based on reports of 54,998 people who have side effects when taking Levaquin from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 337 drugs and 975 conditions by eHealthMe. Check the latest studies of Brain herniation.

On Jul, 21, 2026

54,998 people reported to have side effects when taking Levaquin.
Among them, 17 people (0.03%) have Brain herniation.

Among these 17 people:

How long have people been on Levaquin when they have Brain herniation? *

What is the gender of people who have Brain herniation when taking Levaquin? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Brain herniation when taking Levaquin? *

What are other drugs people take besides Levaquin? *

What are other side effects people have besides Brain herniation? *

Cerebral Haemorrhage (bleeding within the brain): 6 people, 35.29%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 4 people, 23.53%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 4 people, 23.53%
Fall: 3 people, 17.65%
Subdural Haematoma (blood collects between the skull and the surface of the brain): 3 people, 17.65%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 17.65%
Atelectasis (partial or complete collapse of the lung): 3 people, 17.65%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 17.65%
Head Injury: 2 people, 11.76%
Headache (pain in head): 2 people, 11.76%

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 17.65%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Fever: 2 people, 11.76%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 5.88%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 1 person, 5.88%
Breast Cancer Female: 1 person, 5.88%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.88%
Cryptococcosis (potentially fatal fungal disease): 1 person, 5.88%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 5.88%
Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and have Brain herniation?

- Check whether Brain herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levaquin:

Levaquin (56,638 reports)

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain herniation:

Brain herniation (337 drugs)

Browse all the conditions that are associated with Brain herniation:

Brain herniation (975 conditions)

Related publications that referenced our studies

Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin (the active ingredients of Levaquin) and Levaquin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.