Cefazolin and Subarachnoid haemorrhage - a phase IV clinical study of FDA data

Summary:

Subarachnoid haemorrhage is reported as a side effect among people who take Cefazolin (cefazolin sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tacrolimus, and have Pathogen resistance.

The phase IV clinical study analyzes which people have Subarachnoid haemorrhage when taking Cefazolin. It is created by eHealthMe based on reports of 15,127 people who have side effects when taking Cefazolin from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Subarachnoid haemorrhage?

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain) is found to be associated with 841 drugs and 1,020 conditions by eHealthMe. Check the latest studies of Subarachnoid haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

15,127 people reported to have side effects when taking Cefazolin.
Among them, 44 people (0.29%) have Subarachnoid haemorrhage.

Could Cefazolin cause Subarachnoid haemorrhage?

Among these 44 people:

How long have people been on Cefazolin when they have Subarachnoid haemorrhage? *

What is the gender of people who have Subarachnoid haemorrhage when taking Cefazolin? *

female: 30.95 %
male: 69.05 %

What is the age of people who have Subarachnoid haemorrhage when taking Cefazolin? *

What are other drugs people take besides Cefazolin? *

Mycophenolate Mofetil: 13 people, 29.55%
Methylprednisolone: 13 people, 29.55%
Meropenem: 13 people, 29.55%
Tacrolimus: 13 people, 29.55%
Vancomycin: 12 people, 27.27%
Insulin: 11 people, 25.00%
Acetylsalicylic Acid: 9 people, 20.45%
Piperacillin And Tazobactam: 8 people, 18.18%
Acetaminophen: 6 people, 13.64%
Pantoprazole: 5 people, 11.36%

What are other side effects people have besides Subarachnoid haemorrhage? *

Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 24 people, 54.55%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 15 people, 34.09%
Haemorrhage Intracranial (bleeding within the skull): 14 people, 31.82%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 29.55%
Depressed Level Of Consciousness: 13 people, 29.55%
Intraventricular Haemorrhage (intraventricular bleeding): 13 people, 29.55%
Cardiogenic Shock (inadequate circulation of blood): 13 people, 29.55%
Subdural Haemorrhage (bleeding between the skull and the surface of the brain): 12 people, 27.27%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 12 people, 27.27%
Strongyloidiasis (infection with strongyloides stercoralis): 12 people, 27.27%

What are the existing conditions these people have? *

Pathogen Resistance: 12 people, 27.27%
Empyema (collection of pus in a cavity in the body): 10 people, 22.73%
Diabetes: 10 people, 22.73%
Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 9 people, 20.45%
Pneumonia: 3 people, 6.82%
Diabetes Mellitus Inadequate Control: 3 people, 6.82%
Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 6.82%
Blood Potassium Decreased: 3 people, 6.82%
High Blood Pressure: 3 people, 6.82%
Transplant Rejection (a transplant material is not worked): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Cefazolin and have Subarachnoid haemorrhage?

- Check whether Subarachnoid haemorrhage is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cefazolin:

Cefazolin (15,157 reports)

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Subarachnoid haemorrhage:

Subarachnoid haemorrhage (841 drugs)

Browse all the conditions that are associated with Subarachnoid haemorrhage:

Subarachnoid haemorrhage (1,020 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefazolin sodium (the active ingredients of Cefazolin) and Cefazolin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.