Ceftriaxone and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Ceftriaxone (ceftriaxone sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Ceftriaxone. It is created by eHealthMe based on reports of 40,872 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,000 drugs and 1,436 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On May, 01, 2026

40,872 people reported to have side effects when taking Ceftriaxone.
Among them, 69 people (0.17%) have Hyperthyroidism.

Could Ceftriaxone cause Hyperthyroidism?

Among these 69 people:

How long have people been on Ceftriaxone when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Ceftriaxone? *

female: 73.85 %
male: 26.15 %

What is the age of people who have Hyperthyroidism when taking Ceftriaxone? *

What are other drugs people take besides Ceftriaxone? *

What are other side effects people have besides Hyperthyroidism? *

Nausea (feeling of having an urge to vomit): 37 people, 53.62%
Diarrhea: 36 people, 52.17%
Electrolyte Imbalance: 34 people, 49.28%
Agitation (state of anxiety or nervous excitement): 34 people, 49.28%
Erythema Multiforme (a type of hypersensitivity reaction): 33 people, 47.83%
Respiratory Disorder (respiratory disease): 32 people, 46.38%
Cholecystitis (infection of gallbladder): 30 people, 43.48%
Gallstones (stone formation by bile component): 30 people, 43.48%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 27 people, 39.13%
Dermatitis Exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 26 people, 37.68%

What are the existing conditions these people have? *

Dyspnea (difficult or laboured breathing): 34 people, 49.28%
Fever: 34 people, 49.28%
High Blood Pressure: 34 people, 49.28%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 33 people, 47.83%
Pain: 31 people, 44.93%
Agitation (state of anxiety or nervous excitement): 31 people, 44.93%
Nausea (feeling of having an urge to vomit): 31 people, 44.93%
Cholecystitis (infection of gallbladder): 30 people, 43.48%
Diabetes: 29 people, 42.03%
Hyperlipidaemia (presence of excess lipids in the blood): 28 people, 40.58%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftriaxone and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ceftriaxone:

Ceftriaxone (40,991 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,832 reports)

Browse all side effects of Ceftriaxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,000 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,436 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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